Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2909587 | 0.85 | GABRA1 (0.43) | GABRA1GABRB2KDM4EMEN1LMNA | |
| SCHEMBL7237379 | 0.81 | KDM4E (0.40) | GABRA1GABRB2KDM4EMEN1LMNA | |
| SCHEMBL22829541 | 0.78 | GABRA1 (0.40) | GABRA1GABRB2KDM4EMEN1LMNA | |
| SCHEMBL4818959 | 0.77 | GABRA1 (0.46) | GABRA1GABRB2KDM4EMEN1LMNA | |
| SCHEMBL4761487 | 0.72 | KMT2A (0.45) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL9272904 | 0.72 | GABRA1 (0.41) | GABRA1GABRB2KDM4EMEN1LMNA | |
| SCHEMBL2909585 | 0.71 | GABRA1 (0.64) | GABRA1GABRB2KDM4EMEN1LMNA | |
| SCHEMBL7237376 | 0.71 | GABRA1 (0.46) | GABRA1GABRB2KDM4EMEN1LMNA | |
| SCHEMBL14738811 | 0.70 | ESR1 (0.40) | GABRA1GABRB2KDM4EMEN1LMNA | |
| SCHEMBL29703331 | 0.70 | ESR1 (0.40) | GABRA1GABRB2KDM4EMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2008069212-A | THIOETHER FLUORENE SKELETON-CONTAINING POLYMER AND METHOD FOR PRODUCING THE SAME | TOKYO INSTITUTE OF TECHNOLOGY | 2008-03-27 | — | — | JP | disclosed |