Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 2/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TLR2 | O60603 | 8/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25837482 | 0.94 | PLA2G10 (0.47) | PLA2G10PLA2G2ATDP1L3MBTL1TLR2 | |
| SCHEMBL1217267 | 0.91 | TSHR (0.42) | PLA2G10PLA2G2ATDP1L3MBTL1TSHR | |
| SCHEMBL21398746 | 0.91 | TSHR (0.42) | PLA2G10PLA2G2ATDP1L3MBTL1TSHR | |
| SCHEMBL21398845 | 0.91 | TSHR (0.42) | PLA2G10PLA2G2ATDP1L3MBTL1TSHR | |
| SCHEMBL10038814 | 0.90 | TSHR (0.44) | PLA2G10PLA2G2ATDP1L3MBTL1TSHR | |
| SCHEMBL25078776 | 0.87 | PLA2G10 (0.55) | PLA2G10PLA2G2ATLR2LPAR1LPAR3 | |
| SCHEMBL13997509 | 0.87 | PLA2G10 (0.55) | PLA2G10PLA2G2ATLR2LPAR1LPAR3 | |
| SCHEMBL25078765 | 0.87 | PLA2G10 (0.55) | PLA2G10PLA2G2ATLR2LPAR1LPAR3 | |
| SCHEMBL2411920 | 0.87 | PLA2G10 (0.55) | PLA2G10PLA2G2ATLR2LPAR1LPAR3 | |
| SCHEMBL4368865 | 0.87 | PLA2G10 (0.55) | PLA2G10PLA2G2ATLR2LPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7321059-B2 | Compounds for use as surfactants | GLAXO GROUP LIMITED (GB) | 2008-01-22 | — | — | US | disclosed |
| EP-1436007-B1 | COMPOUNDS FOR USE AS SURFACTANTS | GLAXO GROUP LTD (GB) | 2005-03-30 | — | — | EP | disclosed |
| US-20050048024-A1 | Compounds for use as surfactants | GLAXO GROUP LIMITED (GB) | 2005-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050048024-A1 | Compounds for use as surfactants | SGMS1, AQP1, F12 | PLA2G10 731/4885PLA2G2A 2319/4885TDP1 2003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.