Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.89 |
| ▸ | CA4 | P22748 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL19836 | 1.00 | — | — | |
| Acetic Acid SCHEMBL15661806 | 0.95 | CA1 (0.80) | CA1CA4LMNATSHRTHPO | |
| Acetic Acid SCHEMBL2466189 | 0.95 | CA1 (0.80) | CA1CA4LMNATSHRTHPO | |
| Acetic Acid SCHEMBL41209 | 0.95 | CA1 (0.80) | CA1CA4LMNATSHRTHPO | |
| Acetic Acid SCHEMBL4820466 | 0.95 | CA1 (0.80) | CA1CA4LMNATSHRTHPO | |
| Acetic Acid SCHEMBL25274010 | 0.95 | CA1 (0.90) | CA1CA4LMNATSHRTHPO | |
| Acetic Acid SCHEMBL1179482 | 0.95 | CA1 (0.80) | CA1CA4LMNATSHRTHPO | |
| Acetic Acid SCHEMBL10379308 | 0.95 | CA1 (0.80) | CA1CA4LMNATSHRTHPO | |
| Acetic Acid SCHEMBL5484349 | 0.95 | CA1 (0.80) | CA1CA4LMNATSHRTHPO | |
| Acetic Acid SCHEMBL563051 | 0.95 | CA1 (0.80) | CA1CA4LMNATSHRTHPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106745332-B | Combustion method quickly prepares nanometer spinel type nickel ion doped material | 云南民族大学 | 2019-03-08 | — | — | CN | claimed |
| CN-1381915-A | Process for preparing LiMnO and its doped compound | TANG XINCUN (CN) | 2002-11-27 | — | — | CN | claimed |
| WO-2023097065-A1 | LARGE-SCALE SYNTHESIS OF POWDERS OF SOLID-STATE ELECTROLYTE MATERIAL PARTICLES FOR SOLID-STATE BATTERIES, SYSTEMS AND METHODS THEREOF | eJoule, Inc. (US) | 2023-06-01 | — | — | WO | disclosed |
| CN-104685677-B | Positive electrode active material for secondary battery and method for producing same | 株式会社LG化学 | 2018-04-27 | — | — | CN | disclosed |
| CN-104685677-A | Positive electrode active material for secondary battery and method for producing same | LG CHEMICAL LTD | 2015-06-03 | — | — | CN | disclosed |
| CN-101090722-B | Analgesic | TORAY INDUSTRIES, INC. (JP) | 2011-12-21 | — | — | CN | disclosed |
| US-7394091-B2 | Composite nano-particle and method for preparing the same | KEIO UNIVERSITY FACULTY OF SCIENCE AND TECHNOLOGY (JP) | 2008-07-01 | — | — | US | disclosed |
| CN-101090722-A | Analgesic | TORAY INDUSTRIES (JP) | 2007-12-19 | — | — | CN | disclosed |
| CN-1326261-C | Method for preparing layered LiMnO and doping compound | GUANGZHOU RES INST OF NON FERR (CN) | 2007-07-11 | — | — | CN | disclosed |
| US-20060234417-A1 | Composite nanoparticle and process for producing the same | KEIO UNIVERSITY FACULTY OF SCIENCE AND TECHNOLOGY (JP) | 2006-10-19 | — | — | US | disclosed |
| CN-1731600-A | Method for preparing layered LiMnO and doping compound | GUANGZHOU RES INST NONFERROUS (CN) | 2006-02-08 | — | — | CN | disclosed |
| CN-1381915-A | Process for preparing LiMnO and its doped compound | TANG XINCUN (CN) | 2002-11-27 | — | — | CN | disclosed |