Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 19/20 | 0.35 |
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1326756 | 0.94 | SCN9A (0.34) | PDE10A | |
| SCHEMBL1327259 | 0.86 | SCN9A (0.37) | PDE10A | |
| SCHEMBL1327051 | 0.84 | PDE10A (0.34) | MAOBPDE10A | |
| SCHEMBL1328544 | 0.84 | SCN9A (0.37) | — | |
| SCHEMBL1327910 | 0.83 | SCN9A (0.43) | — | |
| SCHEMBL1327605 | 0.82 | C5AR1 (0.36) | PDE10A | |
| SCHEMBL2143361 | 0.81 | MAPT (0.36) | — | |
| SCHEMBL1329062 | 0.81 | PDE10A (0.34) | PDE10A | |
| SCHEMBL2141113 | 0.81 | ALDH1A1 (0.35) | MAOB | |
| SCHEMBL2138201 | 0.79 | CBLB (0.33) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7342115-B2 | Binding antagonist and arylpyridine for antiinflammatory agents, cardiovascular disorders and antagonist or agonist and for immunology | NEUROGEN CORPORATION (US) | 2008-03-11 | — | — | US | disclosed |