Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 5/20 | 0.33 |
| ▸ | CTSL | P07711 | 3/20 | 0.33 |
| ▸ | CTSS | P25774 | 3/20 | 0.33 |
| ▸ | CTSC | P53634 | 3/20 | 0.33 |
| ▸ | CTSZ | Q9UBR2 | 3/20 | 0.33 |
| ▸ | CTSV | O60911 | 2/20 | 0.33 |
| ▸ | CTSH | P09668 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | KLK4 | Q9Y5K2 | 2/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CASP4 | P49662 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | IDH2 | P48735 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4821037 | 1.00 | IDH1 (0.33) | IDH1CTSLCTSSCTSCCTSZ | |
| SCHEMBL14218664 | 0.86 | ADORA1 (0.36) | IDH1CTSSCTSKIDH2 | |
| SCHEMBL5530434 | 0.82 | HTT (0.36) | HTT | |
| SCHEMBL14000735 | 0.80 | IDH1 (0.31) | IDH1IDH2 | |
| SCHEMBL4835877 | 0.80 | IDH1 (0.33) | IDH1IDH2RAB9A | |
| SCHEMBL5101875 | 0.78 | MDM2 (0.35) | — | |
| SCHEMBL2833122 | 0.78 | KDM4E (0.33) | IDH1LMNAIDH2RAB9A | |
| SCHEMBL2833125 | 0.78 | KDM4E (0.33) | IDH1LMNAIDH2RAB9A | |
| SCHEMBL5109371 | 0.77 | MAPK1 (0.33) | MAPK1 | |
| SCHEMBL4818860 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465735-B2 | crop protection agents for controlling harmful fungi; improved activity; 6-chloro-2-(N'-isopropylidene-hydrazino)-5-(2,4,6-trifluorophenyl)pyrimidine-4-yl]-((S)-1-trifluoromethylethyl)amine; against Septoria Leaf Blotch of Wheat, Net Blotch of Barley and Mildew of Cucumber | BASF AKTIENGESELLSCHAFT (DE) | 2008-12-16 | — | — | US | disclosed |
| US-7465735-B2 | crop protection agents for controlling harmful fungi; improved activity; 6-chloro-2-(N'-isopropylidene-hydrazino)-5-(2,4,6-trifluorophenyl)pyrimidine-4-yl]-((S)-1-trifluoromethylethyl)amine; against Septoria Leaf Blotch of Wheat, Net Blotch of Barley and Mildew of Cucumber | BASF AKTIENGESELLSCHAFT (DE) | 2008-12-16 | — | — | US | disclosed |
| US-7449471-B2 | 5-phenylpyrimidines, their preparation, compositions comprising them and their use | BASF AKTIENGESELLSCHAFT (DE) | 2008-11-11 | — | — | US | disclosed |
| US-7449471-B2 | 5-phenylpyrimidines, their preparation, compositions comprising them and their use | BASF AKTIENGESELLSCHAFT (DE) | 2008-11-11 | — | — | US | disclosed |
| US-7449471-B2 | 5-phenylpyrimidines, their preparation, compositions comprising them and their use | BASF AKTIENGESELLSCHAFT (DE) | 2008-11-11 | — | — | US | disclosed |
| US-7375108-B2 | 2-substituted pyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2008-05-20 | — | — | US | disclosed |
| US-7375108-B2 | 2-substituted pyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2008-05-20 | — | — | US | disclosed |
| US-7317015-B2 | 2-Substituted pyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2008-01-08 | — | — | US | disclosed |
| US-7317015-B2 | 2-Substituted pyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2008-01-08 | — | — | US | disclosed |
| US-20070149551-A1 | 5-PHENYLPYRIMIDINES, THEIR PREPARATION, COMPOSITIONS COMPRISING THEM AND THEIR USE | GYPSER ANDREAS | 2007-06-28 | — | — | US | disclosed |
| US-20070129380-A1 | 2-Substituted pyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2007-06-07 | — | — | US | disclosed |
| US-20070105873-A1 | 2-Substituted pyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2007-05-10 | — | — | US | disclosed |
| US-20070105873-A1 | 2-Substituted pyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2007-05-10 | — | — | US | disclosed |
| EP-1651618-B1 | 2-SUBSTITUTED PYRIMIDINES | BASF AG (DE) | 2007-01-03 | — | — | EP | disclosed |
| EP-1651618-A1 | 2-SUBSTITUTED PYRIMIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2006-05-03 | — | — | EP | disclosed |
| EP-1651617-A1 | 2-SUBSTITUTED PYRIMIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2006-05-03 | — | — | EP | disclosed |
| WO-2005019187-A1 | 2-SUBSTITUTED PYRIMIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2005-03-03 | — | — | WO | disclosed |
| WO-2005012261-A1 | 2-SUBSTITUTED PYRIMIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2005-02-10 | — | — | WO | disclosed |
| EP-1448532-A1 | 5-PHENYLPYRIMIDINES, AGENTS COMPRISING THE SAME, METHOD FOR PRODUCTION AND USE THEREOF | BASF Aktiengesellschaft (DE) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003043993-A1 | 5-PHENYLPYRIMIDINES, AGENTS COMPRISING THE SAME, METHOD FOR PRODUCTION AND USE THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 2003-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129380-A1 | 2-Substituted pyrimidines | C5, C3AR1, C1R | IDH1 486/4885CTSL 2227/4885CTSS 2185/4885 |
| US-20070105873-A1 | 2-Substituted pyrimidines | TYMP, RRM2, TYMS | IDH1 763/4885CTSL 2726/4885CTSS 3384/4885 |
| US-20070149551-A1 | 5-PHENYLPYRIMIDINES, THEIR PREPARATION, COMPOSITIONS COMPRISING THEM AND THEIR USE | CBR1, CBR3, NTPCR | IDH1 102/4885CTSL 4758/4885CTSS 4841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.