Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 5/20 | 0.33 |
| ▸ | IDH2 | P48735 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5752604 | 0.87 | BCL6 (0.33) | MEN1ALDH1A1MAPTPKMRAB9A | |
| SCHEMBL13114687 | 0.82 | IDH1 (0.39) | IDH1IDH2MEN1ALDH1A1KMT2A | |
| SCHEMBL3568691 | 0.82 | IDH1 (0.39) | IDH1IDH2MEN1ALDH1A1KMT2A | |
| SCHEMBL14000746 | 0.82 | IDH1 (0.34) | IDH1IDH2 | |
| SCHEMBL14000744 | 0.81 | LMNA (0.30) | — | |
| SCHEMBL4835814 | 0.81 | LMNA (0.30) | — | |
| SCHEMBL4835820 | 0.81 | LMNA (0.30) | — | |
| SCHEMBL14000735 | 0.81 | IDH1 (0.31) | IDH1IDH2 | |
| SCHEMBL14561497 | 0.80 | IDH1 (0.31) | IDH1IDH2 | |
| SCHEMBL5109371 | 0.80 | MAPK1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465735-B2 | crop protection agents for controlling harmful fungi; improved activity; 6-chloro-2-(N'-isopropylidene-hydrazino)-5-(2,4,6-trifluorophenyl)pyrimidine-4-yl]-((S)-1-trifluoromethylethyl)amine; against Septoria Leaf Blotch of Wheat, Net Blotch of Barley and Mildew of Cucumber | BASF AKTIENGESELLSCHAFT (DE) | 2008-12-16 | — | — | US | disclosed |
| US-7465735-B2 | crop protection agents for controlling harmful fungi; improved activity; 6-chloro-2-(N'-isopropylidene-hydrazino)-5-(2,4,6-trifluorophenyl)pyrimidine-4-yl]-((S)-1-trifluoromethylethyl)amine; against Septoria Leaf Blotch of Wheat, Net Blotch of Barley and Mildew of Cucumber | BASF AKTIENGESELLSCHAFT (DE) | 2008-12-16 | — | — | US | disclosed |
| US-7465735-B2 | crop protection agents for controlling harmful fungi; improved activity; 6-chloro-2-(N'-isopropylidene-hydrazino)-5-(2,4,6-trifluorophenyl)pyrimidine-4-yl]-((S)-1-trifluoromethylethyl)amine; against Septoria Leaf Blotch of Wheat, Net Blotch of Barley and Mildew of Cucumber | BASF AKTIENGESELLSCHAFT (DE) | 2008-12-16 | — | — | US | disclosed |
| US-7449471-B2 | 5-phenylpyrimidines, their preparation, compositions comprising them and their use | BASF AKTIENGESELLSCHAFT (DE) | 2008-11-11 | — | — | US | disclosed |
| US-7449471-B2 | 5-phenylpyrimidines, their preparation, compositions comprising them and their use | BASF AKTIENGESELLSCHAFT (DE) | 2008-11-11 | — | — | US | disclosed |
| US-7449471-B2 | 5-phenylpyrimidines, their preparation, compositions comprising them and their use | BASF AKTIENGESELLSCHAFT (DE) | 2008-11-11 | — | — | US | disclosed |
| US-20070149551-A1 | 5-PHENYLPYRIMIDINES, THEIR PREPARATION, COMPOSITIONS COMPRISING THEM AND THEIR USE | GYPSER ANDREAS | 2007-06-28 | — | — | US | disclosed |
| US-20070149551-A1 | 5-PHENYLPYRIMIDINES, THEIR PREPARATION, COMPOSITIONS COMPRISING THEM AND THEIR USE | GYPSER ANDREAS | 2007-06-28 | — | — | US | disclosed |
| US-20070149551-A1 | 5-PHENYLPYRIMIDINES, THEIR PREPARATION, COMPOSITIONS COMPRISING THEM AND THEIR USE | GYPSER ANDREAS | 2007-06-28 | — | — | US | disclosed |
| US-20070054929-A1 | 2-Substituted pyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2007-03-08 | — | — | US | disclosed |
| US-20070054929-A1 | 2-Substituted pyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2007-03-08 | — | — | US | disclosed |
| US-20060148764-A1 | 5-phenypyrimidines their preparation compositions comprising them and their use | BASF AKTIENGESELLSCHAFT (DE) | 2006-07-06 | — | — | US | disclosed |
| EP-1448532-A1 | 5-PHENYLPYRIMIDINES, AGENTS COMPRISING THE SAME, METHOD FOR PRODUCTION AND USE THEREOF | BASF Aktiengesellschaft (DE) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003043993-A1 | 5-PHENYLPYRIMIDINES, AGENTS COMPRISING THE SAME, METHOD FOR PRODUCTION AND USE THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 2003-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149551-A1 | 5-PHENYLPYRIMIDINES, THEIR PREPARATION, COMPOSITIONS COMPRISING THEM AND THEIR USE | CBR1, CBR3, NTPCR | IDH1 102/4885IDH2 397/4885MEN1 4453/4885 |
| US-20060148764-A1 | 5-phenypyrimidines their preparation compositions comprising them and their use | CBR1, CBR3, NT5C | IDH1 181/4885IDH2 592/4885MEN1 4485/4885 |
| US-20070054929-A1 | 2-Substituted pyrimidines | TYMP, TYMS, RPIA | IDH1 246/4885IDH2 273/4885MEN1 2516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.