Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 4/20 | 0.46 |
| ▸ | MAP3K11 | Q16584 | 3/20 | 0.41 |
| ▸ | EEF2K | O00418 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL481861 | 0.81 | MTOR (0.67) | MTORMAP3K11EEF2K | |
| SCHEMBL481860 | 0.81 | MTOR (0.67) | MTORMAP3K11EEF2K | |
| SCHEMBL976654 | 0.79 | MAP3K11 (0.53) | MTORMAP3K11EEF2K | |
| SCHEMBL481716 | 0.76 | MAP3K11 (0.51) | MTORMAP3K11EEF2K | |
| SCHEMBL481717 | 0.76 | MAP3K11 (0.51) | MTORMAP3K11EEF2K | |
| SCHEMBL977455 | 0.75 | MTOR (0.61) | MTORMAP3K11 | |
| SCHEMBL977646 | 0.73 | MTOR (0.63) | MTORMAP3K11 | |
| SCHEMBL482194 | 0.71 | MAP3K11 (0.49) | MTORMAP3K11EEF2K | |
| SCHEMBL482193 | 0.71 | MAP3K11 (0.49) | MTORMAP3K11EEF2K | |
| SCHEMBL481624 | 0.66 | MAP3K11 (0.41) | MTORMAP3K11EEF2K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2078016-B1 | HETEROARYL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | SIGNAL PHARM LLC (US) | 2012-02-01 | — | — | EP | disclosed |