Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL274213 | 1.00 | LMNA (0.44) | LMNASMN1; SMN2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL14209159 | 0.89 | LMNA (0.42) | LMNASMN1; SMN2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL273823 | 0.89 | LMNA (0.56) | LMNASMN1; SMN2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL272849 | 0.89 | LMNA (0.44) | LMNASMN1; SMN2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL14209208 | 0.88 | LMNA (0.55) | LMNASMN1; SMN2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL14209157 | 0.87 | LMNA (0.42) | LMNASMN1; SMN2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL14209202 | 0.86 | LMNA (0.42) | LMNASMN1; SMN2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL14364833 | 0.86 | NPC1 (0.41) | LMNASMN1; SMN2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL30402262 | 0.86 | NPC1 (0.41) | LMNASMN1; SMN2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL868689 | 0.86 | NPC1 (0.41) | LMNASMN1; SMN2CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001299-A2 | FUNGICIDAL ACTIVE SUBSTANCE COMBINATIONS | Bayer CropScience Aktiengesellschaft (DE) | 2008-12-17 | — | — | EP | disclosed |
| WO-2007110173-A2 | FUNGICIDAL ACTIVE SUBSTANCE COMBINATIONS | BAYER CROPSCIENCE AG (DE) | 2007-10-04 | — | — | WO | disclosed |