Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6367927 | 0.82 | CYP2D6 (0.37) | HTT | |
| SCHEMBL19101444 | 0.82 | — | — | |
| SCHEMBL9921756 | 0.78 | ALDH1A1 (0.38) | ALDH1A1GAASMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL17393082 | 0.78 | ALDH1A1 (0.38) | ALDH1A1GAASMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL3634951 | 0.77 | CYP2D6 (0.33) | HTT | |
| SCHEMBL19139482 | 0.76 | ALDH1A1 (0.37) | ALDH1A1GAASMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL6893345 | 0.76 | ALDH1A1 (0.41) | ALDH1A1GAASMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL5839782 | 0.76 | ALDH1A1 (0.37) | ALDH1A1GAASMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL16975487 | 0.76 | ALDH1A1 (0.41) | ALDH1A1GAASMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL16565660 | 0.76 | ALDH1A1 (0.37) | ALDH1A1GAASMN1; SMN2POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 208 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119708521-A | Preparation method and application of lung organ targeted branched poly (beta-amino ester) based mRNA (messenger ribonucleic acid) compound nano particles | 复旦大学附属儿科医院 | 2025-03-28 | — | — | CN | claimed |
| CN-119409987-A | Hyperbranched poly (beta-amino ester), preparation method, composite nanoparticle and application | 复旦大学附属儿科医院 | 2025-02-11 | — | — | CN | claimed |
| CN-119161574-A | Functional star poly (beta-amino ester), preparation method thereof and mRNA delivery application | 上海艾迪特基因科技有限公司 | 2024-12-20 | — | — | CN | claimed |
| CN-117736435-B | Star-shaped poly (beta-amino ester) taking polyamine as core, composite nano particle based on star-shaped poly (beta-amino ester) and preparation method and application of composite nano particle | 上海艾迪特基因科技有限公司 | 2024-06-28 | — | — | CN | claimed |
| CN-117736435-A | Star-shaped poly (beta-amino ester) taking polyamine as core, composite nano particle based on star-shaped poly (beta-amino ester) and preparation method and application of composite nano particle | 上海艾迪特基因科技有限公司 | 2024-03-22 | — | — | CN | claimed |
| CN-116903856-A | Trifunctional branched unit linked poly (beta-amino ester), preparation method and application for delivering apoptosis gene | 上海艾迪特基因科技有限公司 | 2023-10-20 | — | — | CN | claimed |
| CN-116789961-A | Endoplasmic reticulum targeted single-chain cyclic poly (beta-amino ester), preparation method and application | 复旦大学附属儿科医院 | 2023-09-22 | — | — | CN | claimed |
| CN-115703731-A | Imide compound and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-02-17 | — | — | CN | claimed |
| CN-113929904-B | Functional single-chain cyclic poly (beta-amino ester), preparation method thereof and application of gene delivery drug | 西安交通大学 | 2022-10-25 | — | — | CN | claimed |
| CN-113929904-A | Functional single-chain cyclic poly (beta-amino ester), preparation method thereof and application of gene delivery drug | 西安交通大学 | 2022-01-14 | — | — | CN | claimed |
| CN-104768993-B | Method for preparing composite component | 科思创德国股份有限公司 | 2018-02-16 | — | — | CN | claimed |
| CN-103890059-B | Fiber strengthened poly-isocyanurate part and its manufacture method | 科思创德国股份有限公司 | 2017-07-18 | — | — | CN | claimed |
| CN-106061967-A | Heteroaryl substituted nicotinamide compounds | 百时美施贵宝公司 | 2016-10-26 | — | — | CN | claimed |
| CN-104768993-A | Method for producing composite components | BAYER MATERIALSCIENCE AG | 2015-07-08 | — | — | CN | claimed |
| CN-103890059-A | FIBRE-REINFORCED POLYISOCYANURATE COMPONENT AND A METHOD FOR PRODUCTION THEREOF | BAYER IP GMBH | 2014-06-25 | — | — | CN | claimed |
| US-7138530-B2 | Thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2006-11-21 | — | — | US | claimed |
| US-20050234081-A1 | Novel thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions | SUBASINGHE NALIN | 2005-10-20 | — | — | US | claimed |
| US-20040009995-A1 | Novel thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2004-01-15 | — | — | US | claimed |
| CN-119708521-A | Preparation method and application of lung organ targeted branched poly (beta-amino ester) based mRNA (messenger ribonucleic acid) compound nano particles | 复旦大学附属儿科医院 | 2025-03-28 | — | — | CN | disclosed |
| US-4347330-A | OPEN-CELL POLYURETHANE FOAM; POLYSILOXANE-POLYOXYALKYLENE, POLYMETHYLSILOXANE, POLYOXYETHYLENE POLYETHER CELL MODIFIERS | BASF WYANDOTTE CORPORATION (US) | 1982-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234081-A1 | Novel thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions | C5, C9, C1R | ALDH1A1 3674/4885GAA 3751/4885SMN1; SMN2 934/4885 |
| US-20040009995-A1 | Novel thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions | C5, C9, C1R | ALDH1A1 2779/4885GAA 4035/4885SMN1; SMN2 1725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.