Hydrochloric Acid

Hydrochloric Acid

SCHEMBL4823314

Cc1cc(C2=Cc3ccccc3C2[Zr+2](C2C(c3cc(C)cc4ccccc34)=Cc3ccccc32)[SiH](C)C)c2ccccc2c1.[Cl-].[Cl-]

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.36
CYP2A6 P11509 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7140827 0.89 CYP1A2 (0.30) CYP1A2CYP2A6
Hydrochloric Acid SCHEMBL5397360 0.85 MAPT (0.33)
Hydrochloric Acid SCHEMBL5612648 0.83 CYP1A2 (0.36) CYP1A2CYP2A6
Hydrochloric Acid SCHEMBL6435339 0.79 CYP1A2 (0.33) CYP1A2CYP2A6
Hydrochloric Acid SCHEMBL7196886 0.78 CYP1A2 (0.40) CYP1A2CYP2A6
Hydrochloric Acid SCHEMBL8426784 0.78 CYP1A2 (0.40) CYP1A2CYP2A6
Hydrochloric Acid SCHEMBL6706321 0.78 CYP1A2 (0.36) CYP1A2CYP2A6
Hydrochloric Acid SCHEMBL15556763 0.78 NPC1 (0.31)
Hydrochloric Acid SCHEMBL6438723 0.77 CYP1A2 (0.31) CYP1A2CYP2A6
SCHEMBL8505252 0.77 CYP1A2 (0.36) CYP1A2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7326756-B2 High temperature bulk polymerization of branched crystalline polypropylene EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-02-05 US claimed
US-7319125-B2 Supercritical polymerization process and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-01-15 US disclosed
EP-1546223-A2 SUPERCRITICAL POLYMERIZATION PROCESS AND POLYMERS PRODUCED THEREFROM ExxonMobil Chemical Patents Inc. (US) 2005-06-29 EP disclosed
WO-2004106394-A1 COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-12-09 WO disclosed
US-20040242814-A1 COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2004-12-02 US disclosed
WO-2004026923-A9 SUPERCRITICAL POLYMERIZATION PROCESS AND POLYMERS PRODUCED THEREFROM EXXONMOBIL CHEM PATENTS INC (US) 2004-09-10 WO disclosed
US-20040122191-A1 Supercritical polymerization process and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC 2004-06-24 US disclosed
WO-2004026923-A2 SUPERCRITICAL POLYMERIZATION PROCESS AND POLYMERS PRODUCED THEREFROM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-04-01 WO disclosed
US-6613845-B1 Propylene/ethylene-α-olefin block copolymer and process for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-09-02 US disclosed
US-6548628-B2 Molding a polyolefin that has been prepared by means of metallocene catalysts. BASELL POLYOLEFINE GMBH (DE) 2003-04-15 US disclosed
US-20020182428-A1 FILMS AND LAYERS EQUISTAR CHEMICALS, LP 2002-12-05 US disclosed