Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 3/20 | 0.40 |
| ▸ | TLR1 | Q15399 | 3/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4819036 | 0.76 | MPL (0.49) | MPLKDM1AALDH1A1 | |
| SCHEMBL2658617 | 0.75 | ALDH1A1 (0.45) | ALDH1A1HIF1AMAPT | |
| SCHEMBL25335900 | 0.74 | PIK3CA (0.58) | — | |
| SCHEMBL30554566 | 0.74 | PIK3CA (0.58) | — | |
| SCHEMBL826630 | 0.74 | TSHR (0.50) | ALDH1A1KDM4EMAPTNPSR1 | |
| SCHEMBL25372192 | 0.73 | MEN1 (0.44) | KIF11TLR2TLR1ALDH1A1KDM4E | |
| SCHEMBL14106061 | 0.72 | MPL (0.46) | MPLKDM1AALDH1A1SCN9AKDM4E | |
| SCHEMBL2653522 | 0.72 | CCR1 (0.49) | ALDH1A1HIF1AMAPT | |
| SCHEMBL30503070 | 0.71 | MAPT (0.51) | ALDH1A1HIF1AKDM4EMAPTNPSR1 | |
| SCHEMBL2646693 | 0.71 | MAPT (0.51) | ALDH1A1HIF1AKDM4EMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7402345-B2 | Electroluminescent iridium compounds with fluorinated phenylpyridine ligands, and devices made with such compounds | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-22 | — | — | US | disclosed |
| US-7402345-B2 | Electroluminescent iridium compounds with fluorinated phenylpyridine ligands, and devices made with such compounds | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-22 | — | — | US | disclosed |
| US-7402345-B2 | Electroluminescent iridium compounds with fluorinated phenylpyridine ligands, and devices made with such compounds | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-22 | — | — | US | disclosed |
| US-20060054861-A1 | Electroluminescent iridium compounds with fluorinated phenylpyridine ligands, and devices made with such compounds | E. I. DU PONT DE NEMOURS AND COMPANY | 2006-03-16 | — | — | US | disclosed |