Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.59 |
| ▸ | TYR | P14679 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LPL | P06858 | 6/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | TACR2 | P21452 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7876139 | 1.00 | LIPG (0.59) | LIPGTYRTP53CYP3A4MEN1 | |
| SCHEMBL7876152 | 1.00 | LIPG (0.59) | LIPGTYRTP53CYP3A4MEN1 | |
| SCHEMBL29957652 | 1.00 | LIPG (0.59) | LIPGTYRTP53CYP3A4MEN1 | |
| SCHEMBL6291363 | 1.00 | LIPG (0.59) | LIPGTYRTP53CYP3A4MEN1 | |
| SCHEMBL8746456 | 1.00 | LIPG (0.59) | LIPGTYRTP53CYP3A4MEN1 | |
| SCHEMBL29952781 | 1.00 | LIPG (0.59) | LIPGTYRTP53CYP3A4MEN1 | |
| SCHEMBL5892520 | 0.98 | LIPG (0.56) | LIPGTYRTP53CYP3A4MEN1 | |
| SCHEMBL29951685 | 0.98 | LIPG (0.56) | LIPGTYRTP53CYP3A4MEN1 | |
| SCHEMBL3140999 | 0.93 | LIPG (0.49) | LIPGTYRTP53CYP3A4MEN1 | |
| SCHEMBL7208785 | 0.92 | LIPG (0.51) | LIPGTYRTP53CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7462427-B2 | Liquid crystal compounds with branched or cyclic end groups | QINETIQ LIMITED (GB) | 2008-12-09 | — | — | US | disclosed |
| US-7351452-B2 | Liquid crystalline compounds containing a biphenyl core | QINETIQ LIMITED (GB) | 2008-04-01 | — | — | US | disclosed |
| US-20050001200-A1 | Liquid crystalline compounds containing a biphenyl core | QINETIQ LIMITED (GB) | 2005-01-06 | — | — | US | disclosed |
| US-20040206933-A1 | Liquid crystal compounds with branched or cyclic end groups | QINETIQ LIMITED (GB) | 2004-10-21 | — | — | US | disclosed |
| WO-2003040812-A1 | LIQUID CRYSTAL COMPOUNDS, LIQUID CRYSTAL MIXTURES CONTAINING THEM AND LIQUID CRYSTAL DEVICES | QINETIQ LIMITED (GB) | 2003-05-15 | — | — | WO | disclosed |
| WO-2003040074-A1 | LIQUID CRYSTALLINE COMPOUNDS CONTAINING A BIPHENYL CORE | QINETIQ LIMITED (GB) | 2003-05-15 | — | — | WO | disclosed |
| WO-2003024903-A1 | LIQUID CRYSTAL COMPOUNDS WITH BRANCHED OR CYCLIC END GROUPS | QINETIQ LIMITED (GB) | 2003-03-27 | — | — | WO | disclosed |
| EP-1144546-A3 | FLUORINATED TERPHENYLS | QinetiQ Limited (GB) | 2002-08-28 | — | — | EP | disclosed |
| EP-1144546-A2 | FLUORINATED TERPHENYLS | QinetiQ Limited (GB) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000004111-A2 | FLUORINATED TERPHENYLS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 2000-01-27 | — | — | WO | disclosed |
| US-5683623-A | FERROELECTRIC LIQUID CRYSTALS CELLS AND DEVICES FOR ELECTROOPTICAL APPARATUS | CENTRAL RESEARCH LABORATORIES LIMITED (GB) | 1997-11-04 | — | — | US | disclosed |
| EP-0662114-B1 | DIOXANE DERIVATIVES | CENTRAL RESEARCH LAB LTD (GB) | 1997-02-19 | — | — | EP | disclosed |
| EP-0662114-A1 | DIOXANE DERIVATIVES. | CENTRAL RESEARCH LAB LTD (GB) | 1995-07-12 | — | — | EP | disclosed |
| WO-1994006885-A1 | DIOXANE DERIVATIVES | CENTRAL RESEARCH LABORATORIES LIMITED (GB) | 1994-03-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050001200-A1 | Liquid crystalline compounds containing a biphenyl core | YBX1, AFF1, AFF2 | LIPG 4089/4885TYR 2166/4885TP53 1984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.