Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIFC1 | Q9BW19 | 9/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.43 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.42 |
| ▸ | ECE1 | P42892 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4823683 | 1.00 | KIFC1 (0.49) | KIFC1MMECDK2ITGB1ITGA4 | |
| SCHEMBL4829768 | 0.92 | KIFC1 (0.51) | KIFC1MMECDK2ITGB1ITGA4 | |
| SCHEMBL4829763 | 0.92 | KIFC1 (0.51) | KIFC1MMECDK2ITGB1ITGA4 | |
| SCHEMBL4827800 | 0.92 | KIFC1 (0.58) | KIFC1CDK2ITGB1ITGA4GPR34 | |
| SCHEMBL4827802 | 0.92 | KIFC1 (0.58) | KIFC1CDK2ITGB1ITGA4GPR34 | |
| SCHEMBL4832021 | 0.91 | KIFC1 (0.55) | KIFC1CDK2ITGB1ITGA4GPR34 | |
| SCHEMBL4832015 | 0.91 | KIFC1 (0.55) | KIFC1CDK2ITGB1ITGA4GPR34 | |
| SCHEMBL4831602 | 0.91 | KIFC1 (0.48) | KIFC1MMECDK2ITGB1ITGA4 | |
| SCHEMBL4831606 | 0.91 | KIFC1 (0.48) | KIFC1MMECDK2ITGB1ITGA4 | |
| SCHEMBL3972237 | 0.90 | KIFC1 (0.59) | KIFC1MMECDK2ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7459472-B2 | Aryl and heteroaryl compounds, compositions, and methods of use | TRANSTECH PHARMA, INC. (US) | 2008-12-02 | — | — | US | disclosed |