SCHEMBL4823716

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5804138	0.96	MEN1 (0.59)	MEN1KMT2ANPC1GFERMAPT
	SCHEMBL92372	0.80	MEN1 (0.76)	MEN1KMT2ANPC1GFERMAPT
	SCHEMBL3528649	0.80	MEN1 (0.46)	MEN1KMT2ANPC1MAPTSMN1; SMN2
	SCHEMBL7237292	0.79	MEN1 (0.74)	MEN1KMT2ANPC1GFERMAPT
	SCHEMBL2324045	0.78	KMT2A (0.50)	MEN1KMT2ANPC1GFERMAPT
	SCHEMBL1743265	0.76	HSD17B1 (0.47)	MEN1KMT2ANPC1MAPTRAB9A
	SCHEMBL16907820	0.76	HTT (0.52)	HPGDALDH1A1
	SCHEMBL2073317	0.76	HIF1A (0.46)	NPC1SMN1; SMN2LMNAHPGDRAB9A
	SCHEMBL14626743	0.76	KMT2A (0.68)	MEN1KMT2ANPC1GFERMAPT
	SCHEMBL21198240	0.74	HIF1A (0.42)	MAPTKDM4ELMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.