Sugi Predict

Sugi Predict / Compounds / SCHEMBL482375

SCHEMBL482375

SCHEMBL482375

Nc1cc(O)c2ccccc2n1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ BACE1 P56817 2/20 0.60
▸ NCF1 P14598 11/20 0.53
▸ KDM4E B2RXH2 2/20 0.50
▸ ALDH1A1 P00352 2/20 0.50
▸ GLA P06280 2/20 0.50
▸ HPGD P15428 2/20 0.50
▸ CASP1 P29466 2/20 0.50
▸ CASP7 P55210 2/20 0.50
▸ SMN1; SMN2 Q16637 2/20 0.50
▸ HSD17B10 Q99714 2/20 0.50
▸ ACHE P22303 2/20 0.50
▸ CYP1A2 P05177 1/20 0.50
▸ CHRM2 P08172 1/20 0.50
▸ ADRA2A P08913 1/20 0.50
▸ ADORA3 P0DMS8 1/20 0.50
▸ CHRM1 P11229 1/20 0.50
▸ NQO2 P16083 1/20 0.50
▸ MAOA P21397 1/20 0.50
▸ DRD1 P21728 1/20 0.50
▸ SLC6A2 P23975 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31667822 1.00 BACE1 (0.60) BACE1NCF1KDM4EALDH1A1GLA
Water SCHEMBL25301752 0.98 BACE1 (0.58) BACE1NCF1KDM4EALDH1A1GLA
SCHEMBL27739430 0.80 BACE1 (0.51) BACE1NCF1KDM4EALDH1A1GLA
SCHEMBL64767 0.78 MYC (0.52) KDM4EALDH1A1GLAHPGDCASP1
SCHEMBL29690490 0.78 NCF1 (0.64) BACE1NCF1KDM4EALDH1A1GLA
SCHEMBL323374 0.78 NCF1 (0.64) BACE1NCF1KDM4EALDH1A1GLA
SCHEMBL9326676 0.78 MYC (0.52) KDM4EALDH1A1GLAHPGDCASP1
SCHEMBL29376440 0.78 MYC (0.52) KDM4EALDH1A1GLAHPGDCASP1
SCHEMBL832149 0.78 BACE1 (0.58) BACE1NCF1KDM4EALDH1A1GLA
SCHEMBL15472860 0.78 GAA (0.47) BACE1KDM4EALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104597194-B The high performance liquid chromatography-fluorescence method of 3-chlorine-1,2-propylene glycol 武汉轻工大学 2016-07-06 — — CN claimed
CN-104597194-A High performance liquid chromatography-fluorescence detection method for 3-chloro-1,2-propylene glycol UNIV WUHAN POLYTECHNIC 2015-05-06 — — CN claimed
US-4349671-A Process for the production of metal complexes of isoindoline azines CIBA-GEIGY CORPORATION (US) 1982-09-14 — — US claimed
US-4247699-A REACTION OF AN ISATOIC ANHYDRIDE WITH MALONONITRILE FOLLOWED BY TREATMENT WITH A STRONG ACID OR BASE PFIZER INC. (US) 1981-01-27 — — US claimed
US-20250367283-A1 MEVALONATE PATHWAY INHIBITOR AS HIGHLY-EFFICIENT VACCINE ADJUVANT TSINGHUA UNIVERSITY (CN) 2025-12-04 — — US disclosed
US-20250186456-A1 PYRIMIDINE-FUSED CYCLIC COMPOUND AND PREPARATION METHOD AND USE THEREOF GENFLEET THERAPEUTICS (SHANGHAI) INC. (CN) 2025-06-12 — — US disclosed
WO-2025053850-A1 COVALENT KRAS-BINDING COMPOUNDS FOR MEDICAL TREATMENT HYKU BIOSCIENCES INC. (US) 2025-03-13 — — WO disclosed
CN-119097698-A Inhibitors of mevalonate pathway as efficient vaccine adjuvants 清华大学 2024-12-10 — — CN disclosed
CN-114848656-B Inhibitors of mevalonate pathway as efficient vaccine adjuvants 清华大学 2024-09-27 — — CN disclosed
EP-4397664-A1 PYRIMIDINE-FUSED CYCLIC COMPOUND AND PREPARATION METHOD AND USE THEREOF Genfleet Therapeutics (Shanghai) Inc. (CN) 2024-07-10 — — EP disclosed
CN-118090684-A Reagent and method for rapid colorimetric fluorescence detection of mercury ions, iron ions, copper ions and zinc ions 石河子大学 2024-05-28 — — CN disclosed
CN-117916245-A Pyrimidine ring compound and preparation method and application thereof 劲方医药科技(上海)有限公司 2024-04-19 — — CN disclosed
US-4247699-A REACTION OF AN ISATOIC ANHYDRIDE WITH MALONONITRILE FOLLOWED BY TREATMENT WITH A STRONG ACID OR BASE PFIZER INC. (US) 1981-01-27 — — US disclosed
US-4247699-A REACTION OF AN ISATOIC ANHYDRIDE WITH MALONONITRILE FOLLOWED BY TREATMENT WITH A STRONG ACID OR BASE PFIZER INC. (US) 1981-01-27 — — US disclosed
US-4175193-A INTERMEDIATES FOR 1-OXO-1H-6-ALKOXYPYRIMDO(1,2-A)QUINOLINE-2-CARBOXYLIC ACID AND ESTER ANTIALLERGENS PFIZER INC. (US) 1979-11-20 — — US disclosed
US-4175193-A INTERMEDIATES FOR 1-OXO-1H-6-ALKOXYPYRIMDO(1,2-A)QUINOLINE-2-CARBOXYLIC ACID AND ESTER ANTIALLERGENS PFIZER INC. (US) 1979-11-20 — — US disclosed
US-4075343-A Anti-allergenic 5-alkoxyimidazo[1,2-A]quinoline-2-carboxylic acids and derivatives thereof PFIZER INC. (US) 1978-02-21 — — US disclosed
US-4066766-A 1-Oxo-6-substituted pyrimido [1,2-a]quinoline-2-carboxylic acids and derivatives thereof and their use as antiallergy agents PFIZER INC. (US) 1978-01-03 — — US disclosed
US-4031217-A PYRIMIDINE-QUINOLINE COMPOUNDS PFIZER INC. (US) 1977-06-21 — — US disclosed
US-4014881-A ANTIULCER AGENTS PFIZER INC. (US) 1977-03-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250186456-A1 PYRIMIDINE-FUSED CYCLIC COMPOUND AND PREPARATION METHOD AND USE THEREOF KRAS, NRAS, TP53 BACE1 1874/4885NCF1 1358/4885KDM4E 3944/4885
US-20250367283-A1 MEVALONATE PATHWAY INHIBITOR AS HIGHLY-EFFICIENT VACCINE ADJUVANT COASY, GGPS1, HMGCR BACE1 2650/4885NCF1 3414/4885KDM4E 2746/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.