Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14269046 | 0.83 | CNR1 (1.00) | CNR1 | |
| SCHEMBL4823901 | 0.77 | CNR1 (0.72) | CNR1 | |
| SCHEMBL4450848 | 0.77 | CNR1 (1.00) | CNR1 | |
| SCHEMBL3999845 | 0.75 | CNR1 (0.66) | CNR1 | |
| SCHEMBL4465958 | 0.73 | CNR1 (0.69) | CNR1 | |
| SCHEMBL4816393 | 0.72 | CNR1 (0.68) | CNR1 | |
| SCHEMBL15646615 | 0.71 | NPC1 (0.70) | CNR1 | |
| SCHEMBL10669948 | 0.71 | KMT2A (0.76) | CNR1 | |
| SCHEMBL14269034 | 0.70 | CNR1 (0.72) | CNR1 | |
| SCHEMBL14294138 | 0.70 | CNR1 (1.00) | CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7326706-B2 | Pyrazine modulators of cannabinoid receptors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-02-05 | — | — | US | disclosed |
| US-7326706-B2 | Pyrazine modulators of cannabinoid receptors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-02-05 | — | — | US | disclosed |
| US-7326706-B2 | Pyrazine modulators of cannabinoid receptors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-02-05 | — | — | US | disclosed |
| US-20050054659-A1 | Pyrazine modulators of cannabinoid receptors | BRISTOL-MYERS SQUIBB COMPANY | 2005-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050054659-A1 | Pyrazine modulators of cannabinoid receptors | CNR1, CNR2, GPR18 | CNR1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.