SCHEMBL4825

SCHEMBL4825

Nc1nccc(=O)[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6215876 0.75
SCHEMBL755723 0.70
Thiouracil SCHEMBL2856254 0.70
Uracil SCHEMBL877869 0.70
SCHEMBL11359888 0.70
SCHEMBL1919869 0.70
SCHEMBL27998660 0.70
SCHEMBL83773 0.70
Diaminopyrimidine SCHEMBL6961664 0.70
SCHEMBL1356363 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 16572 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106497-A2 FUNCTIONALIZED CIRCULAR RNA AND METHODS AND INTERMEDIATES FOR THEIR PRODUCTION SIEĆ BADAWCZA ŁUKASIEWICZ – PORT POLSKI OSRODEK ROZWOJU TECHNOLOGII (PL) 2026-05-21 WO claimed
WO-2026106907-A1 FAST PCR BY TANDEM PRIMER EMBEDDED WITH RIBONUCLEOTIDE CEPHEID (US) 2026-05-21 WO claimed
CN-122060234-A Preparation method of self-repairing epoxidized natural rubber composite material based on four-fold hydrogen bond-four sulfur bond cooperation 上海工程技术大学 2026-05-19 CN claimed
US-12624374-B1 Processes using nucleoside triphosphates with stable aminoxy groups FIREBIRD BIOMOLECULAR SCIENCES (US) 2026-05-12 US claimed
WO-2026090528-A2 CIRCULARLY STRUCTURED GUIDE RNAS FOR CRISPR GENOME EDITING UNIVERSITY OF MASSACHUSETTS (US) 2026-04-30 WO claimed
EP-4731784-A2 NICK INITIATED CYCLING EMISSION AND REPLACEMENT REACTION Seqonce Biosciences, Inc. (US) 2026-04-29 EP claimed
EP-4720304-A2 IMPROVED MODULAR PRIME EDITING WITH MODIFIED EFFECTORS AND TEMPLATES University of Massachusetts (US) 2026-04-08 EP claimed
US-12596118-B2 Oligonucleotides for inducing paternal UBE3A expression HOFFMANN-LA ROCHE INC. (US) 2026-04-07 US claimed
EP-4713458-A2 COMPOSITIONS AND METHODS FOR REGULATING EXPRESSION OF ATXN2 Riboway Therapeutics, Inc. (US) 2026-03-25 EP claimed
EP-4709860-A1 COMPOSITIONS AND METHODS FOR IMPROVED GENOME EDITING WITH NME2CAS9 AND NME2-SMUCAS9 VARIANTS University of Massachusetts (US) 2026-03-18 EP claimed
EP-0433188-A1 Possibly thermotropic polymolecular associations based on hydrogen bonded monomers, process for their preparation and monomers for carrying out this process RHONE-POULENC CHIMIE (FR) 1991-06-19 EP claimed
EP-0234494-B1 ISOHEXIDE NUCLEOSIDES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS Heinrich Mack Nachf. (DE) 1991-03-13 EP claimed
CN-1044094-A 2-AMINOPYRIMIDINONE DERIVATIVES JANSSEN PHARMACEUTICA NV (BE) 1990-07-25 CN claimed
CN-1044099-A The 2-aminopyrimidinone derivatives JANSSEN PHARMACEUTICA NV (BE) 1990-07-25 CN claimed
EP-0378255-A2 2-Aminopyrimidinone derivatives JANSSEN PHARMACEUTICA N.V. (BE) 1990-07-18 EP claimed
EP-0378254-A2 2-Aminopyrimidinone derivatives JANSSEN PHARMACEUTICA N.V. (BE) 1990-07-18 EP claimed
US-4806542-A VIRISTATICS, IMMUNOSTIMULANTS HEINRICH MACK NACHF. (DE) 1989-02-21 US claimed
US-4523015-A Process and nitroaminopyrimidone intermediates for histamine H2 -antagonists SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1985-06-11 US claimed
EP-0004793-B1 2-NITRO AMINOPYRIMIDONE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE TO PREPARE 2-AMINOPYRIMIDONE DERIVATIVES WHICH HAVE HISTAMINE H2-ANTAGONIST ACTIVITY SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1981-12-30 EP claimed
EP-0004793-A2 2-nitro aminopyrimidone derivatives, a process for their preparation and their use to prepare 2-aminopyrimidone derivatives which have histamine H2-antagonist activity SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1979-10-17 EP claimed