⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2130711 | 0.70 | MAPK1 (0.53) | — | |
| Thiouracil SCHEMBL2856254 | 0.70 | — | — | |
| SCHEMBL27998660 | 0.70 | — | — | |
| SCHEMBL6215876 | 0.70 | — | — | |
| SCHEMBL755723 | 0.70 | — | — | |
| SCHEMBL4825 | 0.70 | — | — | |
| Uracil SCHEMBL877869 | 0.70 | — | — | |
| SCHEMBL1919869 | 0.70 | — | — | |
| SCHEMBL11359888 | 0.70 | — | — | |
| SCHEMBL10927286 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521259-A | Preparation method of chloropyrimidone | 宁夏万博生物科技有限公司 | 2022-12-27 | — | — | CN | claimed |
| CN-1867560-A | 4-pyrimidone derivatives and their use as peptidylpeptidase inhibitors | TAKEDA PHARMACEUTICAL (JP) | 2006-11-22 | — | — | CN | claimed |
| US-6806367-B2 | CHEMICAL INTERMEDIATES; HERBICIDES | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2004-10-19 | — | — | US | claimed |
| US-20030187264-A1 | Process for producing carbonyl hydrazones | ISHIHARA SANGYO KAISHA, LTD. | 2003-10-02 | — | — | US | claimed |
| EP-4169575-B1 | CONDENSED RING COMPOUNDS THAT INHIBIT H-PGDS | SATO PHARMA (JP) | 2026-01-07 | — | — | EP | disclosed |
| CN-115667259-B | Fused ring compounds for inhibiting H-PGDS | 佐藤制药株式会社 | 2025-06-17 | — | — | CN | disclosed |
| US-20250154163-A1 | Pyrimidinone-Containing 17-Beta-Hydroxysteroid Dehydrogenase Type 13 Inhibitors | ENANTA PHARMACEUTICALS, INC. | 2025-05-15 | — | — | US | disclosed |
| WO-2025090868-A1 | PYRIMIDINONE-CONTAINING 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 13 INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2025-05-01 | — | — | WO | disclosed |
| EP-4514805-A1 | PYRIMIDINONE-CONTAINING 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 13 INHIBITORS | Enanta Pharmaceuticals, Inc. (US) | 2025-03-05 | — | — | EP | disclosed |
| WO-2024217500-A1 | ISOQUINOLINE COMPOUND, AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 上海赛默罗生物科技有限公司 | 2024-10-24 | — | — | WO | disclosed |
| CN-118359538-A | Isoquinoline compound, preparation method, pharmaceutical composition and application thereof | 上海赛默罗生物科技有限公司 | 2024-07-19 | — | — | CN | disclosed |
| US-20230416268-A1 | PYRIMIDINONE-CONTAINING 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 13 INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2023-12-28 | — | — | US | disclosed |
| EP-1454910-A1 | Substituted pyrimidinyl-2-(diaza-bicyclo-alkyl)-pyrimidone derivatives | SANOFI-SYNTHELABO (FR) | 2004-09-08 | — | — | EP | disclosed |
| CN-1105113-C | Fungicidal pyrimidinones | DU PONT (US) | 2003-04-09 | — | — | CN | disclosed |
| EP-0836602-B1 | FUNGICIDAL PYRIMIDINONES | DU PONT (US) | 2002-01-30 | — | — | EP | disclosed |
| US-6245770-B1 | AGRICULTURE | E. I. DU PONT DE NEMOURS AND COMPANY | 2001-06-12 | — | — | US | disclosed |
| US-6066638-A | CONTROLLING PLANT DISEASES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-05-23 | — | — | US | disclosed |
| CN-1195345-A | Fungicidal pyrimidinones | DU PONT (US) | 1998-10-07 | — | — | CN | disclosed |
| EP-0836602-A1 | FUNGICIDAL PYRIMIDINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-04-22 | — | — | EP | disclosed |
| WO-1997002262-A1 | FUNGICIDAL PYRIMIDINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-01-23 | — | — | WO | disclosed |