Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 20/20 | 0.60 |
| ▸ | PPARD | Q03181 | 13/20 | 0.60 |
| ▸ | PPARG | P37231 | 11/20 | 0.52 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.51 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.51 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.51 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.51 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.51 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3143612 | 0.84 | PPARA (0.64) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL4825095 | 0.84 | CXCR3 (0.41) | PPARAPPARDPPARG | |
| SCHEMBL3142944 | 0.82 | GPBAR1 (0.40) | PPARAPPARDPPARG | |
| SCHEMBL3948697 | 0.75 | PPARA (1.00) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL6906429 | 0.72 | SMN1; SMN2 (0.51) | PPARAPPARD | |
| SCHEMBL6494547 | 0.70 | PPARA (0.74) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL4041201 | 0.70 | PPARA (1.00) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL3458686 | 0.69 | SMN1; SMN2 (0.55) | PPARAPPARD | |
| SCHEMBL6495524 | 0.69 | PPARA (0.76) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL3946807 | 0.69 | PPARA (1.00) | PPARAPPARDPPARGPSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957073-A2 | MEDICINAL DRUG | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007066784-A2 | DIARYLETHER DERIVATIVES AS ANTITUMOR AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-06-14 | — | — | WO | disclosed |