Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | FAAH | O00519 | 5/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TERT | O14746 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28150363 | 1.00 | TSHR (0.55) | TSHRFAAHEP300KMT2AMEN1 | |
| SCHEMBL811748 | 1.00 | TSHR (0.55) | TSHRFAAHEP300KMT2AMEN1 | |
| SCHEMBL20917075 | 1.00 | TSHR (0.55) | TSHRFAAHEP300KMT2AMEN1 | |
| SCHEMBL4488722 | 0.98 | TSHR (0.52) | TSHRFAAHEP300KMT2AMEN1 | |
| SCHEMBL3267188 | 0.90 | TSHR (0.43) | TSHRLMNAPOLBAPEX1 | |
| SCHEMBL865307 | 0.85 | TSHR (0.38) | TSHRLMNA | |
| SCHEMBL864847 | 0.85 | TSHR (0.38) | TSHRLMNA | |
| SCHEMBL866222 | 0.85 | TSHR (0.38) | TSHRLMNA | |
| SCHEMBL865301 | 0.85 | TSHR (0.38) | TSHRLMNA | |
| SCHEMBL865640 | 0.85 | TSHR (0.38) | TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2047837-B1 | Dental adhesive and use thereof | KERR CORP (US) | 2016-04-13 | — | — | EP | claimed |
| EP-1968528-B1 | DENTAL COMPOSITIONS WITH SURFACE-TREATED FILLER FOR SHELF STABILITY | 3M INNOVATIVE PROPERTIES CO (US) | 2016-02-17 | — | — | EP | claimed |
| EP-3370652-B1 | BONE IMPLANT | ATTENBOROUGH DENTAL LABORATORIES LTD (GB) | 2020-04-01 | — | — | EP | disclosed |
| US-20190239868-A1 | BONE IMPLANT | ATTENBOROUGH DENTAL LABORATORIES LIMITED (GB) | 2019-08-08 | — | — | US | disclosed |
| EP-3370652-A2 | BONE IMPLANT | Attenborough Dental Laboratories Limited (GB) | 2018-09-12 | — | — | EP | disclosed |
| WO-2017077315-A2 | IMPLANT | ATTENBOROUGH DENTAL LABORATORIES LIMITED (GB) | 2017-05-11 | — | — | WO | disclosed |
| US-9463144-B2 | Adhesive composition suitable for dental uses | 3M INNOVATIVE PROPERTIES COMPANY | 2016-10-11 | — | — | US | disclosed |
| US-20130224692-A1 | ADHESIVE COMPOSITION SUITABLE FOR DENTAL USES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-08-29 | — | — | US | disclosed |
| US-7449499-B2 | Self-etching dental compositions and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-11-11 | — | — | US | disclosed |
| US-20050175965-A1 | Self-etching dental compositions and methods | 3M DEUTSCHLAND GMBH (DE) | 2005-08-11 | — | — | US | disclosed |
| EP-1413589-A1 | POLYMERS FOR ORAL USE AND COMPOSITIONS FOR ORAL USE | Kao Corporation (JP) | 2004-04-28 | — | — | EP | disclosed |