Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 7/20 | 0.39 |
| ▸ | CDK8 | P49336 | 7/20 | 0.39 |
| ▸ | CDK19 | Q9BWU1 | 2/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.36 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4829084 | 0.91 | BTK (0.41) | CCNCCDK8CDK19KDM4ENPC1 | |
| SCHEMBL1060125 | 0.91 | BTK (0.41) | CCNCCDK8CDK19KDM4ENPC1 | |
| SCHEMBL4833889 | 0.88 | CCNC (0.42) | CCNCCDK8CDK19KMT2ANPC1 | |
| SCHEMBL4831155 | 0.85 | CCNC (0.44) | CCNCCDK8CDK19NPC1LMNA | |
| SCHEMBL4834355 | 0.85 | CCNC (0.44) | CCNCCDK8CDK19NPC1LMNA | |
| SCHEMBL4831171 | 0.85 | CCNC (0.44) | CCNCCDK8CDK19NPC1LMNA | |
| SCHEMBL4834883 | 0.84 | HDAC1 (0.46) | KDM4EMEN1MAPTKMT2ANPC1 | |
| SCHEMBL4834214 | 0.84 | HDAC1 (0.46) | KDM4EMEN1MAPTKMT2ANPC1 | |
| SCHEMBL4829197 | 0.84 | HDAC1 (0.41) | CCNCCDK8CDK19KDM4EMEN1 | |
| SCHEMBL4834135 | 0.83 | CCNC (0.44) | CCNCCDK8CDK19KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287438-A1 | Agent for preventing or treating neuropathy | MOMOSE YU | 2008-11-20 | — | — | US | disclosed |
| US-7423159-B2 | Agent for preventing or treating neuropathy | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-09 | — | — | US | disclosed |
| US-20060004069-A1 | Agent for preventing or treating neuropathy | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004069-A1 | Agent for preventing or treating neuropathy | NR2C2, NR0B2, NR2E1 | CCNC 2548/4885CDK8 2963/4885CDK19 2585/4885 |
| US-20080287438-A1 | Agent for preventing or treating neuropathy | NR2C2, NR0B2, NR2E1 | CCNC 2548/4885CDK8 2963/4885CDK19 2585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.