⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28014 | 0.94 | ALDH1A1 (0.30) | — | |
| SCHEMBL29561426 | 0.89 | — | — | |
| Fluoride SCHEMBL1399379 | 0.89 | — | — | |
| Water SCHEMBL15666534 | 0.89 | — | — | |
| Water SCHEMBL533765 | 0.89 | — | — | |
| SCHEMBL1143571 | 0.89 | — | — | |
| SCHEMBL5014786 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL1554658 | 0.89 | — | — | |
| Ethyne SCHEMBL20610034 | 0.84 | — | — | |
| SCHEMBL6045462 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071446-A | The organic reaction carried out in aqueous solution in the presence of hydroxy alkyl (alkyl) cellulose or alkylcellulose | 艾伯维德国有限责任两合公司 | 2018-12-21 | — | — | CN | disclosed |
| US-7375229-B2 | Dihydro-dibenzo[B,E]oxepine based selective estrogen receptor modulators, compositions and methods | ELI LILLY AND COMPANY (US) | 2008-05-20 | — | — | US | disclosed |
| US-20060142267-A1 | DIHYDRO-DIBENZO[B,E]OXEPINE BASED SELECTIVE ESTROGEN RECEPTOR MODULATORS, COMPOSITIONS AND METHODS | WALLACE OWEN B | 2006-06-29 | — | — | US | disclosed |
| US-7067510-B2 | Dihydro-dibenzo[b,e]oxepine based selective estrogren receptor modulators, compositions and methods | ELI LILLY AND COMPANY (US) | 2006-06-27 | — | — | US | disclosed |
| EP-1527076-B1 | DIHYDRO-DIBENZO[B,E]OXEPINE BASED SELECTIVE ESTROGEN RECEPTOR MODULATORS, COMPOSITIONS AND METHODS | LILLY CO ELI (US) | 2005-12-28 | — | — | EP | disclosed |
| US-20050240017-A1 | Dihydro-dibenzo[b,e]oxepine based selective estrogren receptor modulators, compositions and methods | ELI LILLY AND COMPANY | 2005-10-27 | — | — | US | disclosed |
| EP-1527076-A1 | DIHYDRO-DIBENZO (B,E) OXEPINE BASED SELECTIVE ESTROGEN RECEPTOR MODULATORS, COMPOSITIONS AND METHODS | ELI LILLY AND COMPANY (US) | 2005-05-04 | — | — | EP | disclosed |
| WO-2004009603-A1 | DIHYDRO-DIBENZO[B,E]OXEPINE BASED SELECTIVE ESTROGEN RECEPTOR MODULATORS, COMPOSITIONS AND METHODS | ELI LILLY AND COMPANY (US) | 2004-01-29 | — | — | WO | disclosed |