⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2422453 | 0.72 | — | — | |
| SCHEMBL269083 | 0.72 | — | — | |
| SCHEMBL2074346 | 0.72 | — | — | |
| SCHEMBL2218552 | 0.72 | — | — | |
| SCHEMBL2427349 | 0.72 | — | — | |
| SCHEMBL4306283 | 0.72 | — | — | |
| SCHEMBL10991808 | 0.72 | — | — | |
| SCHEMBL18243176 | 0.68 | — | — | |
| SCHEMBL4082985 | 0.68 | — | — | |
| SCHEMBL2401857 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 922 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116854683-A | Coumarin thiazole derivative and preparation method and application thereof | 中北大学 | 2023-10-10 | — | — | CN | claimed |
| CN-111018686-B | 6-benzylidene-2-aryl ethynyl cyclohexenone derivative and preparation method and medical application thereof | 南通大学 | 2020-09-22 | — | — | CN | claimed |
| CN-111560019-A | Method for synthesizing isopentenyl adenine or derivatives thereof by one-step method | 安徽京和生物药业科技有限公司 | 2020-08-21 | — | — | CN | claimed |
| CN-111018686-A | 6-benzylidene-2-aryl ethynyl cyclohexenone derivative and preparation method and medical application thereof | 南通大学 | 2020-04-17 | — | — | CN | claimed |
| WO-2019078246-A1 | IDO/TDO INHIBITOR | 一般社団法人ファルマバレープロジェクト支援機構 | 2019-04-25 | — | — | WO | claimed |
| EP-2395993-B1 | SKIN TREATMENT | LEO LABORATORIES LTD (IE) | 2017-06-21 | — | — | EP | claimed |
| US-8084613-B2 | Tetrazoyloxime derivative and plant disease control agent | NIPPON SODA CO., LTD. (JP) | 2011-12-27 | — | — | US | claimed |
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | claimed |
| US-4622413-A | ESTERIFICATION, SALT FORMATION | PPG INDUSTRIES, INC. (US) | 1986-11-11 | — | — | US | claimed |
| US-12043640-B2 | Prodrugs of STAT3 inhibitors | TVARDI THERAPEUTICS, INC. (US) | 2024-07-23 | — | — | US | disclosed |
| US-20240238460-A1 | IMPROVED PROSTATE-SPECIFIC MEMBRANE ANTIGEN TARGETING RADIOPHARMACEUTICALS AND USES THEREOF | TELIX PHARMACEUTICALS INNOVATIONS PTY LTD (AU) | 2024-07-18 | — | — | US | disclosed |
| WO-2024148932-A1 | EGFR C797S MUTATION INHIBITOR AND PHARMACEUTICAL USE THEREOF | 上海和誉生物医药科技有限公司 | 2024-07-18 | — | — | WO | disclosed |
| CN-117480164-B | Factor XIa inhibitor and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2024-07-05 | — | — | CN | disclosed |
| EP-4393922-A1 | IRAK4 DEGRADATION AGENT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Leadingtac Pharmaceutical Co. Ltd. (CN) | 2024-07-03 | — | — | EP | disclosed |
| EP-0110576-A2 | Ionizing radiation-sensitive material and its use for preparing a pattern | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1984-06-13 | — | — | EP | disclosed |
| EP-0023584-B1 | PROCESS FOR THE PREPARATION OF TRIFLUOROMETHYL NAPHTHALENES | BAYER AG (DE) | 1983-01-26 | — | — | EP | disclosed |
| US-4331613-A | Process for the preparation of trifluoromethylnaphthalenes | BAYER AKTIENGESELLSCHAFT (DE) | 1982-05-25 | — | — | US | disclosed |
| EP-0008453-B1 | PROCESS FOR PREPARING TRIFLUOROMETHYL AROMATIC COMPOUNDS | BAYER AG (DE) | 1981-04-29 | — | — | EP | disclosed |
| EP-0023584-A1 | Process for the preparation of trifluoromethyl naphthalenes | BAYER AG (DE) | 1981-02-11 | — | — | EP | disclosed |
| EP-0008453-A1 | Process for preparing trifluoromethyl aromatic compounds | BAYER AG (DE) | 1980-03-05 | — | — | EP | disclosed |