⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2074346 | 0.88 | — | — | |
| SCHEMBL2427968 | 0.78 | — | — | |
| SCHEMBL162934 | 0.72 | — | — | |
| SCHEMBL6230396 | 0.72 | — | — | |
| SCHEMBL482633 | 0.72 | — | — | |
| SCHEMBL2443 | 0.72 | — | — | |
| SCHEMBL830743 | 0.72 | — | — | |
| SCHEMBL6775241 | 0.72 | — | — | |
| SCHEMBL22538 | 0.72 | — | — | |
| SCHEMBL1013573 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106565593-B | A kind of preparation method of Ceritinib intermediate | 常州市勇毅生物药业有限公司 | 2019-03-01 | — | — | CN | claimed |
| CN-110078668-A | A kind of phenylimidazole class XOR inhibitor and preparation and application | 华南理工大学 | 2019-08-02 | — | — | CN | disclosed |
| CN-106565593-B | A kind of preparation method of Ceritinib intermediate | 常州市勇毅生物药业有限公司 | 2019-03-01 | — | — | CN | disclosed |
| US-20090299074-A1 | BENZO[b]THIOPHEN DERIVATIVES AND PROCESS FOR THEIR PRODUCTION | TEIJIN PHARMA LIMITED (JP) | 2009-12-03 | — | — | US | disclosed |
| US-20090264663-A1 | 3-HYDROXYMETHYLBENZO[b]THIOPHENE DERIVATIVES AND PROCESS FOR THEIR PRODUCTION | TEIJEN PHARMA LIMITED (JP) | 2009-10-22 | — | — | US | disclosed |
| US-7494987-B2 | Agent for treating respiratory diseases containing 4-hydroxypiperidine derivative as active ingredient | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2009-02-24 | — | — | US | disclosed |
| EP-1947096-A1 | 3-HYDROXYMETHYLBENZO[b]THIOPHENE DERIVATIVE AND METHOD FOR PRODUCING SAME | Teijin Pharma Limited (JP) | 2008-07-23 | — | — | EP | disclosed |
| EP-1947097-A1 | BENZOÝb¨THIOPHEN DERIVATIVE AND PROCESS FOR PRODUCTION THEREOF | Teijin Pharma Limited (JP) | 2008-07-23 | — | — | EP | disclosed |
| US-20060040985-A1 | Therapeutic agent for treating respiratory diseases containing 4-hydroxypiperidine derivative as active ingredient | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2006-02-23 | — | — | US | disclosed |
| EP-1568688-A1 | THERAPEUTIC AGENT FOR RESPIRATORY DISEASE CONTAINING 4-HYDROXYPIPERIDINE DERIVATIVE AS ACTIVE INGREDIENT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2005-08-31 | — | — | EP | disclosed |