Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL897122 | 0.89 | NPSR1 (0.42) | NPSR1ATMMEN1KMT2AKDM4E | |
| SCHEMBL896887 | 0.85 | NPSR1 (0.44) | NPSR1ATMMEN1KMT2AKDM4E | |
| SCHEMBL896808 | 0.81 | NPSR1 (0.40) | NPSR1ATMMEN1KMT2AKDM4E | |
| SCHEMBL18380971 | 0.67 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL897030 | 0.66 | NPSR1 (0.48) | NPSR1ATMMEN1KMT2AKDM4E | |
| SCHEMBL896576 | 0.65 | CRBN (0.31) | — | |
| SCHEMBL897027 | 0.64 | CYP3A4 (0.38) | ALDH1A1 | |
| SCHEMBL897068 | 0.64 | CRBN (0.49) | NPSR1ATMMEN1KMT2AKDM4E | |
| SCHEMBL1530731 | 0.64 | CRBN (0.61) | — | |
| SCHEMBL896948 | 0.63 | CYP3A4 (0.55) | NPSR1ATMMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411352-A2 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Abbott Laboratories (US) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010111436-A2 | ANTIVIRAL COMPOUNDS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2010-09-30 | — | — | WO | disclosed |