⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11514017 | 0.97 | HDAC4 (0.38) | — | |
| SCHEMBL2384838 | 0.97 | — | — | |
| SCHEMBL11513142 | 0.97 | HDAC4 (0.38) | — | |
| SCHEMBL11515974 | 0.97 | HDAC4 (0.38) | — | |
| SCHEMBL11515968 | 0.97 | HDAC4 (0.38) | — | |
| SCHEMBL11513040 | 0.97 | HDAC4 (0.38) | — | |
| SCHEMBL11713017 | 0.97 | HDAC4 (0.38) | — | |
| SCHEMBL11515969 | 0.97 | HDAC4 (0.38) | — | |
| SCHEMBL11513038 | 0.97 | HDAC4 (0.38) | — | |
| SCHEMBL11713028 | 0.97 | HDAC4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113980036-B | Near infrared fluorescent probe with dual responses of alkalinity, active oxygen and active nitrogen, and preparation method and application thereof | 复旦大学 | 2023-05-30 | — | — | CN | claimed |
| CN-110563696-B | Process for preparing heteroatom-containing cyclohexene halide | 蚌埠产品质量监督检验研究院 | 2022-05-03 | — | — | CN | claimed |
| CN-110563696-A | Process for preparing heteroatom-containing cyclohexene halide | 蚌埠产品质量监督检验研究院 | 2019-12-13 | — | — | CN | claimed |
| EP-3004120-B1 | SPIRO-1,1'-BIINDANE-7,7-BISPHOSPHINE OXIDES AS HIGHLY ACTIVE SUPPORTING LIGANDS FOR PALLADIUM-CATALYZED ASYMMETRIC HECK REACTION | UNIV NANYANG TECH (SG) | 2018-08-29 | — | — | EP | claimed |
| CN-105658656-A | 1, 1' -spiroindane-7, 7-bisphosphine oxides as highly active supporting ligands in palladium-catalyzed asymmetric Heck reactions | 南洋理工大学 | 2016-06-08 | — | — | CN | claimed |
| US-20160136629-A1 | SPIRO-1,1'-BINDANE-7,7-BISPHOSPHINE OXIDES AS HIGHLY ACTIVE SUPPORTING LIGANDS FOR PALADIUM-CATALYZED ASYMMETRIC HECK REACTION | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2016-05-19 | — | — | US | claimed |
| EP-3004120-A1 | SPIRO-1,1'-BIINDANE-7,7-BISPHOSPHINE OXIDES AS HIGHLY ACTIVE SUPPORTING LIGANDS FOR PALLADIUM-CATALYZED ASYMMETRIC HECK REACTION | Nanyang Technological University (SG) | 2016-04-13 | — | — | EP | claimed |
| WO-2014196930-A1 | SPIRO-1,1'-BIINDANE-7,7-BISPHOSPHINE OXIDES AS HIGHLY ACTIVE SUPPORTING LIGANDS FOR PALLADIUM-CATALYZED ASYMMETRIC HECK REACTION | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-12-11 | — | — | WO | claimed |
| EP-1594835-A4 | METHOD OF PREPARATION OF HETEROCYCLIC MOLECULES WITH PHARMACEUTICAL PHARMACEUTICAL EXCIPIENT COSMECEUTICAL AGROCHEMICAL AND INDUSTRIAL USES | AUSPEX PHARMACEUTICALS INC (US) | 2007-05-02 | — | — | EP | claimed |
| US-20060173199-A1 | Method of preparation of heterocyclic molecules with pharmaceutical, pharmaceutical excipient, cosmeceutical, agrochemical and industrial uses | HONG BORCHERNG | 2006-08-03 | — | — | US | claimed |
| EP-1594835-A2 | METHOD OF PREPARATION OF HETEROCYCLIC MOLECULES WITH PHARMACEUTICAL PHARMACEUTICAL EXCIPIENT COSMECEUTICAL AGROCHEMICAL AND INDUSTRIAL USES | Auspex Pharmaceuticals, Inc. (US) | 2005-11-16 | — | — | EP | claimed |
| WO-2004064745-A2 | METHOD OF PREPARATION OF HETEROCYCLIC MOLECULES WITH PHARMACEUTICAL PHARMACEUTICAL EXCIPIENT COSMECEUTICAL AGROCHEMICAL AND INDUSTRIAL USES | AUSPEX PHARMACEUTICALS, INC. (US) | 2004-08-05 | — | — | WO | claimed |
| US-20020165411-A1 | Sterically hindered phosphine ligands and uses thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-11-07 | — | — | US | claimed |
| WO-2002048160-A1 | STERICALLY HINDERED PHOSPHINE LIGANDS AND USES THEREOF | YALE UNIVERSITY (US) | 2002-06-20 | — | — | WO | claimed |
| CN-122055371-A | Faster automated iterative C-C bond formation | 伊利诺伊大学评议会 | 2026-05-15 | — | — | CN | disclosed |
| US-20250388565-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND METHODS OF USE THEREOF | RELAY THERAPEUTICS, INC. | 2025-12-25 | — | — | US | disclosed |
| EP-4551570-A1 | NOVEL COMPOUNDS AS GCN2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | Dong-A ST Co., Ltd. (KR) | 2025-05-14 | — | — | EP | disclosed |
| US-4066834-A | Cycloalkenyl analogues of prostaglandins E | MILES LABORATORIES, INC. (US) | 1978-01-03 | — | — | US | disclosed |
| US-3988358-A | Process for the preparation of carboxylic acid esters from organic halides | THE UNIVERSITY OF DELAWARE (US) | 1976-10-26 | — | — | US | disclosed |
| US-3960932-A | Process for the preparation of aldehydes from organic halides | THE UNIVERSITY OF DELAWARE (US) | 1976-06-01 | — | — | US | disclosed |