Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5902682 | 0.79 | KDM4E (0.43) | MAPTMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL25732175 | 0.76 | CYP19A1 (0.54) | LMNAALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL181713 | 0.76 | KDM4E (0.56) | LMNAALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL8873657 | 0.76 | KDM4E (0.56) | LMNAALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL29657292 | 0.76 | KDM4E (0.56) | LMNAALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL22133117 | 0.75 | HPGD (0.44) | LMNAALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL7743895 | 0.75 | EDNRA (0.53) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7660780 | 0.75 | EDNRA (0.53) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5709329 | 0.75 | SLC6A2 (0.50) | NPC1RAB9ATSHRTP53CYP1A2 | |
| SCHEMBL11128366 | 0.75 | SLC6A2 (0.46) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080119547-A1 | Aminoindane Derivatives As Serotonin And Norepinephrine Uptake Inhibitors | H. LUNDBECK A/S (DK) | 2008-05-22 | — | — | US | disclosed |
| US-7351734-B2 | Aminoindane derivatives as serotonin and norepinephrine uptake inhibitors | H. LUNDBECK A/S (DK) | 2008-04-01 | — | — | US | disclosed |
| US-20050085530-A1 | Aminoindane derivatives as serotonin and norepinephrine uptake inhibitors | H. LUNDBECK A/S (DK) | 2005-04-21 | — | — | US | disclosed |
| CN-1606552-A | Aminoindane derivatives as serotonin and norepinephrine uptake inhibitors | LUNDBECK & CO AS H (DK) | 2005-04-13 | — | — | CN | disclosed |
| EP-1458704-A1 | AMINOINDANE DERIVATIVES AS SEROTONIN AND NOREPINEPHRINE UPTAKE INHIBITORS | H. Lundbeck A/S (DK) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003055873-A1 | AMINOINDANE DERIVATIVES AS SEROTONIN AND NOREPINEPHRINE UPTAKE INHIBITORS | H. LUNDBECK A/S (DK) | 2003-07-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119547-A1 | Aminoindane Derivatives As Serotonin And Norepinephrine Uptake Inhibitors | SLC6A2, SLC18A2, SLC6A4 | LMNA 1939/4885ALDH1A1 812/4885MAPT 597/4885 |
| US-20050085530-A1 | Aminoindane derivatives as serotonin and norepinephrine uptake inhibitors | SLC6A2, SLC18A2, SLC6A4 | LMNA 1995/4885ALDH1A1 766/4885MAPT 713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.