SCHEMBL181713

SCHEMBL181713

O=C1CC(c2ccccc2)c2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.56
EEF2K O00418 1/20 0.53
FGFR1 P11362 1/20 0.46
FGFR2 P21802 1/20 0.46
CYP19A1 P11511 3/20 0.46
HSD17B10 Q99714 2/20 0.46
ADORA3 P0DMS8 1/20 0.46
AR P10275 1/20 0.46
MAOB P27338 1/20 0.46
ALDH1A1 P00352 3/20 0.46
CYP11B2 P19099 1/20 0.45
MAPT P10636 2/20 0.43
LMNA P02545 1/20 0.43
TP53 P04637 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
MAPK1 P28482 1/20 0.43
HTR2B P41595 1/20 0.43
CFTR P13569 1/20 0.43
GOPC Q9HD26 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8873657 1.00 KDM4E (0.56) KDM4EEEF2KFGFR1FGFR2CYP19A1
SCHEMBL29657292 1.00 KDM4E (0.56) KDM4EEEF2KFGFR1FGFR2CYP19A1
SCHEMBL3470602 0.89 KDM4E (0.51) KDM4EEEF2KFGFR1FGFR2CYP19A1
SCHEMBL6591640 0.87 MAOB (0.53) KDM4EEEF2KCYP19A1MAOBHTR2B
SCHEMBL6001645 0.87 RAB9A (0.49) KDM4EEEF2KALDH1A1MAPTLMNA
SCHEMBL10069663 0.83 TNKS2 (0.47) KDM4EEEF2KFGFR1FGFR2CYP19A1
SCHEMBL10069667 0.83 KDM4E (0.46) KDM4EEEF2KMAOBALDH1A1MAPT
SCHEMBL2820666 0.83 KDM4E (0.56) KDM4ECYP19A1MAOBALDH1A1MAPT
SCHEMBL11328036 0.83 AKR1B1 (0.44) KDM4EEEF2KFGFR1FGFR2HSD17B10
SCHEMBL2484478 0.82 DDB1 (0.47) KDM4EEEF2KCYP19A1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080254519-A1 Process for Producing Picolinic Acid Compounds SHINDO KAZUTOSHI 2008-10-16 US claimed
EP-1726645-A1 PROCESS FOR PRODUCING PICOLINIC ACID COMPOUNDS MARINE BIOTECHNOLOGY INSTITUTE CO., LTD. (JP) 2006-11-29 EP claimed
JP-2002500211-A 2002-01-08 JP claimed
US-6268535-B1 REACTING BENZENE SUBSTITUTED UNSATURATED CARBOXYLIC ACID IN PRESENCE OF FRIEDEL-CRAFT CATALYST WITH BENZENE COMPOUND TO FORM 3-ARYL-3-PHENYL-1-PROPANOIC ACID REACTING TO FORM 3-ARYL INDAN; REDUCING, REACTING WITH AMINE TO FORM 3-ARYLINDANAMINE PHARM-ECO LABORATORIES, INC. 2001-07-31 US claimed
EP-1044184-A1 SYNTHESIS OF 3-ARYL-1-INDANAMINES Pharm-Eco Laboratoires, Incorporated (US) 2000-10-18 EP claimed
WO-1999035119-A1 SYNTHESIS OF 3-ARYL-1-INDANAMINES PHARM-ECO LABORATORIES, INC. (US) 1999-07-15 WO claimed
JP-5294889-A None JP disclosed
JP-61005048-A None JP disclosed
EP-4745117-A1 NOVEL INDENONE DERIVATIVE AND USE THEREOF Amyloid Solution Inc. (KR) 2026-05-20 EP disclosed
US-12628554-B2 Photoelectric conversion element, imaging element, optical sensor, and compound FUJIFILM CORPORATION (JP) 2026-05-12 US disclosed
US-12568754-B2 Laminate comprising a wavelength-conversion material and a wavelength-selective absorption layer, display device, and organic electroluminescent display device FUJIFILM CORPORATION (JP) 2026-03-03 US disclosed
US-20250393473-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, AND OPTICAL SENSOR FUJIFILM CORP (JP) 2025-12-25 US disclosed
US-20250374741-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORP (JP) 2025-12-04 US disclosed
EP-0240859-A2 Lipoxygenase inhibiting compounds ABBOTT LABORATORIES (US) 1987-10-14 EP disclosed
JP-S615048-A NOVEL PREPARATION OF O-BENZOYLBENZOIC ACID SUMITOMO CHEM CO LTD 1986-01-10 JP disclosed
US-4548946-A Antiinflammatory and/or analgesic 1,8-Dihydro-(or 3,8-dihydro)-8-aryl-2-[(substituted)thio]-indeno[1,2-d]imidazoles and their corresponding sulfoxides and sulfones E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-10-22 US disclosed
EP-0061712-A1 Antiinflammatory and/or analgesic 1,8-dihydro (or 3,8-dihydro)-8-aryl-2-((substituted)thio)-indeno(1,2-)imidazoles and their corresponding sulfoxides and sulfones E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-10-06 EP disclosed
US-4246281-A ANTIINFLAMMATORY AGENTS LILLY INDUSTRIES LIMITED (GB) 1981-01-20 US disclosed
US-4230850-A HYPOTENSIVE AGENTS, VASODILATION LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) 1980-10-28 US disclosed
US-4151182-A CATALYTIC OXIDATION FROM INDANS OR DIPHENYLMETHANE DERIVATIVES BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DE) 1979-04-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080254519-A1 Process for Producing Picolinic Acid Compounds HPD, PAH, DHPS KDM4E 2986/4885EEF2K 2643/4885FGFR1 287/4885
US-12568754-B2 Laminate comprising a wavelength-conversion material and a wavelength-selective absorption layer, display device, and organic electroluminescent display device STRA6, CDH1, EPCAM KDM4E 657/4885EEF2K 2089/4885FGFR1 3461/4885
US-20250393473-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, AND OPTICAL SENSOR NR2E3, CRY1, CRY2 KDM4E 2101/4885EEF2K 2477/4885FGFR1 778/4885
US-12628554-B2 Photoelectric conversion element, imaging element, optical sensor, and compound SCO2, CRY2, PYM1 KDM4E 2716/4885EEF2K 3492/4885FGFR1 1656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.