Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29950981 | 1.00 | S1PR3 (0.42) | S1PR3THRATHRBNR5A1MEN1 | |
| SCHEMBL8746439 | 1.00 | S1PR3 (0.42) | S1PR3THRATHRBNR5A1MEN1 | |
| SCHEMBL29416793 | 1.00 | S1PR3 (0.42) | S1PR3THRATHRBNR5A1MEN1 | |
| SCHEMBL8218479 | 1.00 | S1PR3 (0.42) | S1PR3THRATHRBNR5A1MEN1 | |
| SCHEMBL7788798 | 1.00 | S1PR3 (0.42) | S1PR3THRATHRBNR5A1MEN1 | |
| SCHEMBL8746471 | 1.00 | S1PR3 (0.42) | S1PR3THRATHRBNR5A1MEN1 | |
| SCHEMBL2510510 | 1.00 | S1PR3 (0.42) | S1PR3THRATHRBNR5A1MEN1 | |
| SCHEMBL29546276 | 1.00 | S1PR3 (0.42) | S1PR3THRATHRBNR5A1MEN1 | |
| SCHEMBL8746461 | 0.98 | L3MBTL1 (0.40) | S1PR3THRATHRBNR5A1MEN1 | |
| SCHEMBL29545875 | 0.98 | L3MBTL1 (0.40) | S1PR3THRATHRBNR5A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114230552-B | Trifluoromethoxy dibenzothiophene, preparation method thereof and preparation method of related intermediate | 江苏广域化学有限公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-114230552-A | Trifluoromethoxy dibenzothiophene, preparation method thereof and preparation method of related intermediate | 江苏广域化学有限公司 | 2022-03-25 | — | — | CN | disclosed |
| US-7462427-B2 | Liquid crystal compounds with branched or cyclic end groups | QINETIQ LIMITED (GB) | 2008-12-09 | — | — | US | disclosed |
| US-7351452-B2 | Liquid crystalline compounds containing a biphenyl core | QINETIQ LIMITED (GB) | 2008-04-01 | — | — | US | disclosed |
| US-20050001200-A1 | Liquid crystalline compounds containing a biphenyl core | QINETIQ LIMITED (GB) | 2005-01-06 | — | — | US | disclosed |
| US-20040206933-A1 | Liquid crystal compounds with branched or cyclic end groups | QINETIQ LIMITED (GB) | 2004-10-21 | — | — | US | disclosed |
| EP-1160233-B1 | Novel terphenyl compounds | SHARP KK (JP) | 2004-07-21 | — | — | EP | disclosed |
| WO-2003040812-A1 | LIQUID CRYSTAL COMPOUNDS, LIQUID CRYSTAL MIXTURES CONTAINING THEM AND LIQUID CRYSTAL DEVICES | QINETIQ LIMITED (GB) | 2003-05-15 | — | — | WO | disclosed |
| WO-2003040074-A1 | LIQUID CRYSTALLINE COMPOUNDS CONTAINING A BIPHENYL CORE | QINETIQ LIMITED (GB) | 2003-05-15 | — | — | WO | disclosed |
| WO-2003024903-A1 | LIQUID CRYSTAL COMPOUNDS WITH BRANCHED OR CYCLIC END GROUPS | QINETIQ LIMITED (GB) | 2003-03-27 | — | — | WO | disclosed |
| WO-1996000710-A1 | NOVEL CHIRAL CYCLOHEXYL COMPOUNDS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 1996-01-11 | — | — | WO | disclosed |
| EP-0662114-A1 | DIOXANE DERIVATIVES. | CENTRAL RESEARCH LAB LTD (GB) | 1995-07-12 | — | — | EP | disclosed |
| US-5417885-A | Antiferroelectric liquid crystal compound | SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) | 1995-05-23 | — | — | US | disclosed |
| EP-0637624-A1 | Antiferroelectric liquid crystal compound | Showa Shell Sekiyu Kabushiki Kaisha (JP) | 1995-02-08 | — | — | EP | disclosed |
| WO-1994029405-A1 | LIQUID CRYSTAL MATERIALS, MIXTURES AND DEVICES | THE SECRETARY OF STATE FOR DEFENCE (GB) | 1994-12-22 | — | — | WO | disclosed |
| WO-1994006885-A1 | DIOXANE DERIVATIVES | CENTRAL RESEARCH LABORATORIES LIMITED (GB) | 1994-03-31 | — | — | WO | disclosed |
| US-5273680-A | A chiral tilted smectic liquid crystal based on terphenyls | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-12-28 | — | — | US | disclosed |
| EP-0329752-B1 | FLUORINATED OLIGOPHENYLS AND THEIR USE IN LIQUID CRYSTAL MATERIALS | MERCK PATENT GmbH (DE) | 1993-03-17 | — | — | EP | disclosed |
| EP-0329752-A1 | FLUORINATED OLIGOPHENYLS AND THEIR USE IN LIQUID CRYSTAL MATERIALS | MERCK PATENT GmbH (DE) | 1989-08-30 | — | — | EP | disclosed |
| WO-1989002425-A1 | FLUORINATED OLIGOPHENYLS AND THEIR USE IN LIQUID CRYSTAL MATERIALS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-03-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050001200-A1 | Liquid crystalline compounds containing a biphenyl core | YBX1, AFF1, AFF2 | S1PR3 3057/4885THRA 3032/4885THRB 2398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.