Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 19/20 | 0.66 |
| ▸ | SMO | Q99835 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4273809 | 0.88 | NR3C1 (0.60) | NR3C1SMOPGR | |
| SCHEMBL4286626 | 0.86 | NR3C1 (0.69) | NR3C1PGR | |
| SCHEMBL4276388 | 0.84 | NR3C1 (0.61) | NR3C1SMOPGR | |
| SCHEMBL4274590 | 0.83 | NR3C1 (0.65) | NR3C1SMOPGR | |
| SCHEMBL4286574 | 0.83 | NR3C1 (0.79) | NR3C1PGR | |
| SCHEMBL4287940 | 0.82 | NR3C1 (0.59) | NR3C1SMO | |
| SCHEMBL4279984 | 0.82 | NR3C1 (0.64) | NR3C1SMOPGR | |
| SCHEMBL4286581 | 0.80 | NR3C1 (0.61) | NR3C1PGR | |
| SCHEMBL3015225 | 0.79 | NR3C1 (0.64) | NR3C1SMOPGR | |
| SCHEMBL4277484 | 0.79 | NR3C1 (0.69) | NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893588-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | Boehringer Ingelheim International GmbH (DE) | 2008-03-05 | — | — | EP | claimed |
| WO-2006135826-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-12-21 | — | — | WO | claimed |