Styrene

Styrene

SCHEMBL4828672

C=Cc1ccccc1.C[N+](C)(C)C

nearest known ligand 0.78

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Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.78
▸ TSHR P16473 2/20 0.78
▸ TDP1 Q9NUW8 2/20 0.46
▸ TP53 P04637 1/20 0.46
▸ HDAC8 Q9BY41 3/20 0.44
▸ MAOB P27338 1/20 0.39
▸ CYP2A6 P11509 1/20 0.39
▸ APOBEC3A P31941 1/20 0.38
▸ APOBEC3G Q9HC16 1/20 0.38
▸ LMNA P02545 1/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.38
▸ CHAT P28329 2/20 0.36
▸ CYP3A4 P08684 1/20 0.35
▸ RELA Q04206 1/20 0.34
▸ AKR1C3 P42330 1/20 0.34
▸ TRPA1 O75762 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL27835963 0.97 ALDH1A1 (0.74) ALDH1A1TSHRTDP1TP53HDAC8
Styrene SCHEMBL28407802 0.91 ALDH1A1 (0.93) ALDH1A1TSHRTDP1TP53HDAC8
Styrene SCHEMBL587422 0.91 ALDH1A1 (0.93) ALDH1A1TSHRTDP1TP53HDAC8
Styrene SCHEMBL11416235 0.91 — —
Styrene SCHEMBL29712924 0.91 — —
Styrene SCHEMBL11495068 0.89 ALDH1A1 (0.78) ALDH1A1TSHRTDP1TP53HDAC8
Styrene SCHEMBL7160606 0.88 ALDH1A1 (0.88) ALDH1A1TSHRTDP1TP53HDAC8
Styrene SCHEMBL29005836 0.88 ALDH1A1 (0.88) ALDH1A1TSHRTDP1TP53HDAC8
Styrene SCHEMBL8336803 0.88 ALDH1A1 (0.88) ALDH1A1TSHRTDP1TP53HDAC8
Styrene SCHEMBL11144289 0.88 ALDH1A1 (1.00) ALDH1A1TSHRTDP1TP53HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107106997-A Grafted ultra-high molecular weight polyethylene microporous membrane 恩特格里斯公司 2017-08-29 — — CN claimed
US-20030191262-A1 Chain transfer agents for raft polymerization in aqueous media UNIVERSITY OF SOUTHERN MISSISSIPPI 2003-10-09 — — US claimed
WO-2003066685-A2 CHAIN TRANSFER AGENTS FOR RAFT POLYMERIZATION IN AQUEOUS MEDIA UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2003-08-14 — — WO claimed
US-5073502-A Method and apparatus for analyzing total organic halogens UNITED TECHNOLOGIES CORPORATION (US) 1991-12-17 — — US claimed
CN-107106997-A Grafted ultra-high molecular weight polyethylene microporous membrane 恩特格里斯公司 2017-08-29 — — CN disclosed
CN-103547655-B Reactive mesogen based polymer particles MERCK PATENT GMBH 2015-06-03 — — CN disclosed
CN-102307912-B Particles for electrophoretic displays MERCK PATENT GMBH 2015-05-27 — — CN disclosed
CN-103547655-A Reactive mesogen based polymer particles MERCK PATENT GMBH 2014-01-29 — — CN disclosed
CN-103068929-A Particles for electrophoretic displays MERCK PATENT GMBH 2013-04-24 — — CN disclosed
CN-102355827-A Method for producing clear and soluble cereal-based extracts HARBOES BRYGGERI AS 2012-02-15 — — CN disclosed
CN-102307914-A Particles for electrophoretic displays MERCK PATENT GMBH 2012-01-04 — — CN disclosed
CN-102307912-A Particles for electrophoretic displays MERCK PATENT GMBH 2012-01-04 — — CN disclosed
US-20060111531-A1 Chain transfer agents for RAFT polymerization in aqueous media UNIVERSITY OF SOUTHERN MISSISSIPPI 2006-05-25 — — US disclosed
US-6855840-B2 Chain transfer agents for raft polymerization in aqueous media UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2005-02-15 — — US disclosed
US-20030195310-A1 Chain transfer agents for raft polymerization in aqueous media UNIVERSITY OF SOUTHERN MISSISSIPPI 2003-10-16 — — US disclosed
US-20030191262-A1 Chain transfer agents for raft polymerization in aqueous media UNIVERSITY OF SOUTHERN MISSISSIPPI 2003-10-09 — — US disclosed
US-6593059-B2 Heat sensitive elements; graft polymer FUJI PHOTO FILM CO., LTD. (JP) 2003-07-15 — — US disclosed
US-20020142247-A1 Planographic printing plate precursor FUJIFILM CORPORATION (JP) 2002-10-03 — — US disclosed
EP-1235105-A2 Planographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2002-08-28 — — EP disclosed
US-5073502-A Method and apparatus for analyzing total organic halogens UNITED TECHNOLOGIES CORPORATION (US) 1991-12-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030195310-A1 Chain transfer agents for raft polymerization in aqueous media TRRAP, NEFM, TMT1A ALDH1A1 746/4885TSHR 2878/4885TDP1 674/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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