SCHEMBL4828773

SCHEMBL4828773

COC(=O)C(C)(OC(C)=O)C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.40
ALDH1A1 P00352 2/20 0.39
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17281573 0.79 DGAT1 (0.39) DGAT1ALDH1A1GAA
SCHEMBL25768043 0.77 GAA (0.38) ALDH1A1GAA
SCHEMBL23998526 0.77 GAA (0.38) ALDH1A1GAA
SCHEMBL6348804 0.76 GAA (0.37) GAA
SCHEMBL6348809 0.76 GAA (0.37) GAA
SCHEMBL23998492 0.76 GAA (0.37) GAA
SCHEMBL7805815 0.74 GAA (0.35) GAA
SCHEMBL11841794 0.72 DGAT1 (0.46) DGAT1ALDH1A1GAA
SCHEMBL1661821 0.72 DGAT1 (0.46) DGAT1ALDH1A1GAA
SCHEMBL4677120 0.72 DGAT1 (0.46) DGAT1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7358027-B2 Used to generate resist images on a substrate, i.e., in the manufacture of integrated circuits INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2008-04-15 US disclosed
US-6730452-B2 TO GENERATE RESIST IMAGES ON A SUBSTRATE IN THE MANUFACTURE OF INTEGRATED CIRCUITS INTERNATIONAL BUSINESS MACHINES CORPORATION 2004-05-04 US disclosed
US-20030186160-A1 Used to generate resist images on a substrate, i.e., in the manufacture of integrated circuits GLOBALFOUNDRIES U.S. INC. 2003-10-02 US disclosed
US-6610456-B2 Such as 4-(hexafluorohydroxyisopropyl)styrene copolymer with tert-butyl alpha-trifluoromethyl acrylate; transparent to deep ultraviolet (DUV) radiation INTERNATIONAL BUSINESS MACHINES CORPORATION 2003-08-26 US disclosed
US-6548219-B2 Transparent to deep ultraviolet (DUV) radiation INTERNATIONAL BUSINESS MACHINES CORPORATION 2003-04-15 US disclosed
US-6509134-B2 Used to generate resist images; in the manufacture of integrated circuits INTERNATIONAL BUSINESS MACHINES CORPORATION 2003-01-21 US disclosed
US-20020164538-A1 Fluorine-containing styrene acrylate copolymers and use thereof in lithographic photoresist compositions INTERNATIONAL BUSINESS MACHINES CORPORATION 2002-11-07 US disclosed
US-20020146638-A1 Norbornene fluoroacrylate copolymers and process for use thereof GLOBALFOUNDRIES U.S. INC. 2002-10-10 US disclosed
US-20020146639-A1 Lithographic photoresist composition and process for its use GLOBALFOUNDRIES U.S. INC. 2002-10-10 US disclosed
US-20020102490-A1 Substituted norbornene fluoroacrylate copolymers and use thereof lithographic photoresist compositions GLOBALFOUNDRIES U.S. INC. 2002-08-01 US disclosed