SCHEMBL482915

SCHEMBL482915

CN(C)c1ccc(C(=O)/C=C/c2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 1.00
CYP1B1 Q16678 8/20 1.00
KMT2A Q03164 6/20 1.00
NPC1 O15118 4/20 1.00
RAB9A P51151 4/20 1.00
SMN1; SMN2 Q16637 2/20 1.00
CASP3 P42574 1/20 1.00
SENP8 Q96LD8 1/20 1.00
SENP7 Q9BQF6 1/20 1.00
SENP6 Q9GZR1 1/20 1.00
TLR9 Q9NR96 2/20 0.74
CRHBP P24387 1/20 0.74
CRHR2 Q13324 1/20 0.74
MAOB P27338 5/20 0.68
LMNA P02545 3/20 0.68
TNFRSF1A P19438 2/20 0.68
PLIN1 O60240 1/20 0.68
BCHE P06276 1/20 0.68
ACHE P22303 1/20 0.68
RECQL P46063 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL482916 1.00 MAPT (1.00) MAPTCYP1B1KMT2ANPC1RAB9A
SCHEMBL3448404 0.93 MAPT (0.88) MAPTCYP1B1KMT2ANPC1RAB9A
SCHEMBL4582427 0.93 MAPT (0.88) MAPTCYP1B1KMT2ANPC1RAB9A
Chalcone SCHEMBL28260009 0.93 MAPT (0.88) MAPTCYP1B1KMT2ANPC1RAB9A
SCHEMBL3448406 0.93 MAPT (0.88) MAPTCYP1B1KMT2ANPC1RAB9A
SCHEMBL2911445 0.91 TLR9 (0.87) MAPTCYP1B1KMT2ANPC1RAB9A
SCHEMBL2911444 0.91 TLR9 (0.87) MAPTCYP1B1KMT2ANPC1RAB9A
SCHEMBL11673489 0.91 MAPT (0.83) MAPTCYP1B1KMT2ANPC1RAB9A
SCHEMBL11673447 0.91 MAPT (0.83) MAPTCYP1B1KMT2ANPC1RAB9A
SCHEMBL11673493 0.91 MAPT (0.83) MAPTCYP1B1KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 267 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0368327-B1 Light-sensitive composition FUJI PHOTO FILM CO LTD (JP) 1995-02-15 EP claimed
US-5202221-A Photocrosslinkable copolymer having maleimido side chain, cyanine dye sensitizer FUJI PHOTO FILM CO., LTD. (JP) 1993-04-13 US claimed
US-5110709-A Photoresists of excellent image resolution FUJI PHOTO FILM CO., LTD. (JP) 1992-05-05 US claimed
US-5002853-A Polymeric Sulfonyloxy-Amides and Iides FUJI PHOTO FILM CO., LTD. (JP) 1991-03-26 US claimed
EP-0363198-A2 Positive working photosensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1990-04-11 EP claimed
US-4148658-A BENZOYLMETHYLENE-BENSOTHIAZOLYIDEND-THIAZOLIDONE COMPOUND, AMINE, AND AMINOARYLCARBONYL COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1979-04-10 US claimed
EP-2618215-B1 Method for producing a lithographic printing plate FUJIFILM CORP (JP) 2017-07-05 EP disclosed
EP-1621337-B1 Image recording material and lithographic printing plate precursor FUJIFILM CORP (JP) 2017-03-22 EP disclosed
EP-1916568-B1 Use of a developing solution for lithographic printing plates and production method of lithographic printing plate FUJIFILM CORP (JP) 2017-02-08 EP disclosed
EP-1696268-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2016-11-09 EP disclosed
EP-3086176-A1 A LITHOGRAPHIC PRINTING METHOD Fujifilm Corporation (JP) 2016-10-26 EP disclosed
EP-3086177-A1 METHOD FOR PREPARING A LITHOGRAPHIC PRINTING PLACE PRECURSOR Fujifilm Corporation (JP) 2016-10-26 EP disclosed
EP-2492338-B1 PLATE CLEANING AGENT FOR LITHOGRAPHIC PRINTING PLATE AND PLATE SURFACE TREATMENT METHOD FOR LITHOGRAPHIC PRINTING PLATE FUJIFILM CORP (JP) 2016-08-24 EP disclosed
EP-0301520-A2 Dry presensitized plate Fuji Photo Film Co., Ltd. (JP) 1989-02-01 EP disclosed
US-4555474-A IMPROVED PHOTOSENSITIVITY USING HETEROCYCLIC KETONE PHOTOINITIATORS; LITHOGRAPHY; PHOTORESISTS FUJI PHOTO FILM CO., LTD. (JP) 1985-11-26 US disclosed
US-4290870-A 5-ISOXOLONE, AROMATIC CARBONYL, DIALKYLAMINO AROMATIC CARBONYL OR FUJI PHOTO FILM CO., LTD. (JP) 1981-09-22 US disclosed
US-4148658-A BENZOYLMETHYLENE-BENSOTHIAZOLYIDEND-THIAZOLIDONE COMPOUND, AMINE, AND AMINOARYLCARBONYL COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1979-04-10 US disclosed
US-4035395-A Process for the preparation of ketones BAYER AKTIENGESELLSCHAFT (DT) 1977-07-12 US disclosed
US-4018606-A Organic azo pigment sensitizers for photoconductive layers EASTMAN KODAK COMPANY (US) 1977-04-19 US disclosed
US-4014889-A Process for preparing ketones BAYER AKTIENGESELLSCHAFT (DT) 1977-03-29 US disclosed