Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.49 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1121833 | 0.90 | CA2 (0.63) | CA2MAPK1ALDH1A1SLC1A1SLC1A2 | |
| SCHEMBL867735 | 0.89 | CA2 (0.67) | CA2MAPK1ALDH1A1SLC1A1SLC1A2 | |
| SCHEMBL191565 | 0.89 | CA2 (0.67) | CA2MAPK1ALDH1A1SLC1A1SLC1A2 | |
| SCHEMBL3128633 | 0.87 | CA2 (0.64) | CA2MAPK1ALDH1A1SLC1A1SLC1A2 | |
| SCHEMBL3824905 | 0.87 | CA2 (0.59) | CA2MAPK1ALDH1A1SLC1A1SLC1A2 | |
| SCHEMBL2230971 | 0.85 | CA2 (0.62) | CA2MAPK1ALDH1A1SLC1A1SLC1A2 | |
| SCHEMBL8830714 | 0.85 | CA2 (0.62) | CA2MAPK1ALDH1A1SLC1A1SLC1A2 | |
| SCHEMBL160551 | 0.84 | GRIK1 (0.62) | CA2MAPK1ALDH1A1SLC1A1SLC1A2 | |
| SCHEMBL592984 | 0.84 | CA2 (0.55) | CA2MAPK1ALDH1A1SLC1A1SLC1A2 | |
| SCHEMBL3993632 | 0.84 | CA2 (0.55) | CA2MAPK1ALDH1A1SLC1A1SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343874-B1 | CELLS COMPRISING LACTYL-COA DEHYDRATASE, 3-HYDROXYPROPIONYL-COA DEHYDRATASE OR A MULTIENZYME COMPLEX ISOLATED FROM MEGASPHAERA ELSDENII AND CHLOROFLEXUS AURANTIACUS FOR THE PRODUCTION OF 3-HYDROXYPROPIONIC ACID | CARGILL INC (US) | 2012-10-03 | — | — | EP | claimed |
| EP-1706457-B1 | PRODUCTION OF 3-HYDROXYPROPIONIC ACID USING BETA-ALANINE/PYRUVATE AMINOTRANSFERASE | NOVOZYMES AS (DK) | 2012-02-01 | — | — | EP | claimed |
| EP-1575881-B1 | ALANINE 2,3- AMINOMUTASE | NOVOZYMES AS (DK) | 2009-05-27 | — | — | EP | claimed |