SCHEMBL482994

SCHEMBL482994

Nc1ccc(S(=O)(=O)O)cc1.Nc1ccc(S(=O)(=O)O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 1.00
ALDH1A1 P00352 3/20 1.00
NT5E P21589 1/20 1.00
LMNA P02545 3/20 0.62
MPO P05164 1/20 0.62
CYP3A4 P08684 1/20 0.62
CYP2C9 P11712 1/20 0.62
HTR6 P50406 1/20 0.62
TDP1 Q9NUW8 4/20 0.59
CA1 P00915 3/20 0.59
CA2 P00918 3/20 0.59
CA12 O43570 2/20 0.59
CA9 Q16790 2/20 0.59
CA14 Q9ULX7 2/20 0.59
AGO2 Q9UKV8 2/20 0.59
USP2 O75604 1/20 0.59
CA4 P22748 1/20 0.59
CA6 P23280 1/20 0.59
CA5A P35218 1/20 0.59
CA7 P43166 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31415204 1.00 TSHR (1.00) TSHRALDH1A1NT5ELMNAMPO
SCHEMBL30495973 1.00 TSHR (1.00) TSHRALDH1A1NT5ELMNAMPO
SCHEMBL24407 1.00 TSHR (1.00) TSHRALDH1A1NT5ELMNAMPO
Water SCHEMBL8586611 0.97 TSHR (0.95) TSHRALDH1A1NT5ELMNAMPO
Hydrochloric Acid SCHEMBL4825957 0.97 TSHR (0.95) TSHRALDH1A1NT5ELMNAMPO
Sulfuric Acid SCHEMBL10596856 0.97 TSHR (0.95) TSHRALDH1A1NT5ELMNAMPO
SCHEMBL7766917 0.97 TSHR (0.95) TSHRALDH1A1NT5ELMNAMPO
SCHEMBL646074 0.97 TSHR (0.95) TSHRALDH1A1NT5ELMNAMPO
SCHEMBL192816 0.97 TSHR (0.95) TSHRALDH1A1NT5ELMNAMPO
Sulfuric Acid SCHEMBL8646805 0.97 TSHR (0.95) TSHRALDH1A1NT5ELMNAMPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112979543-B Substituted 4-phenylpyridines for the treatment of NK-1 receptor related diseases 赫尔森保健股份公司 2024-09-24 CN disclosed
CN-102211912-B Cement-based grouting material containing sulfamate water reducing agent and preparation method thereof MA QINGHAO 2013-01-30 CN disclosed
CN-102092979-B Sulfamate water-reducing agent and preparation method thereof QINGHAO MA 2012-11-14 CN disclosed
US-20120092598-A1 SURFACE MODIFIED ORGANIC BLACK PIGMENTS, SURFACE MODIFIED CARBON BLACKS, PIGMENT MIXTURES USING THEM, AND LOW DIELECTRIC BLACK DISPERSIONS, COATINGS, FILMS, BLACK MATRICES, AND DEBVICES CONTAINING SAME CABOT CORPORATION (US) 2012-04-19 US disclosed
US-20120074068-A1 POLYSACCHARIDE MATRIX HAVING A GRAFTED POLYMER, METHOD FOR PRODUCING THE SAME AND USE THEREOF SARTORIUS STEDIM BIOTECH GMBH (DE) 2012-03-29 US disclosed
EP-2088173-B1 CURABLE COMPOSITION AND CATALYST COMPOSITION KANEKA CORP (JP) 2012-02-22 EP disclosed
EP-0909212-B1 Use and method for use of modified carbon adsorbents CABOT CORP (US) 2012-02-01 EP disclosed
US-8067136-B2 Charge control agent, toner, image forming method, and image forming apparatus CANON KABUSHIKI KAISHA (JP) 2011-11-29 US disclosed
US-8048911-B2 Melanin eliminator preparation OGA Research, Inc. (JP) 2011-11-01 US disclosed
CN-102211912-A Cement-based grouting material containing sulfamate water reducing agent and preparation method thereof QINGHAO MA 2011-10-12 CN disclosed
US-20110177328-A1 IONOMER RESIN, RESIN COMPOSITION COMPRISING THE SAME, AND USES OF THEM MITSUI CHEMICALS, INC. (JP) 2011-07-21 US disclosed
CN-102092979-A Sulfamate water-reducing agent and preparation method thereof QINGHAO MA 2011-06-15 CN disclosed
EP-2322574-A1 IONOMER RESIN, RESIN COMPOSITIONS CONTAINING SAME AND USES OF BOTH Mitsui Chemicals, Inc. (JP) 2011-05-18 EP disclosed
US-20110105668-A1 RUBBER LAMINATE UNIMATEC CO., LTD. (JP) 2011-05-05 US disclosed
US-7935771-B2 Polymer having sulfonic acid group or sulfonic acid ester group and amide group, and toner for developing electrostatic latent image having the polymer CANON KABUSHIKI KAISHA (JP) 2011-05-03 US disclosed
EP-2302000-A1 Curable composition and catalyst composition KANEKA CORPORATION (JP) 2011-03-30 EP disclosed
EP-2292428-A1 RUBBER LAMINATE Unimatec Co., Ltd. (JP) 2011-03-09 EP disclosed
EP-2292670-A2 Charge control agent, toner, image forming method, and image forming apparatus Canon Kabushiki Kaisha (JP) 2011-03-09 EP disclosed
US-20110028658-A1 IONOMER RESIN COMPOSITION AND SHAPED ARTICLE OBTAINED FROM THE RESIN COMPOSITION MITSUI CHEMICALS, INC. (JP) 2011-02-03 US disclosed
EP-2280043-A1 IONOMER RESIN COMPOSITION AND MOLDED ARTICLE OBTAINED FROM THE RESIN COMPOSITION Mitsui Chemicals, Inc. (JP) 2011-02-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120092598-A1 SURFACE MODIFIED ORGANIC BLACK PIGMENTS, SURFACE MODIFIED CARBON BLACKS, PIGMENT MIXTURES USING THEM, AND LOW DIELECTRIC BLACK DISPERSIONS, COATINGS, FILMS, BLACK MATRICES, AND DEBVICES CONTAINING SAME TYR, CDYL, CD99 TSHR 4050/4885ALDH1A1 388/4885NT5E 2070/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.