Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 known ✓ | P50406 | 1/20 | 0.59 |
| ▸ | CA2 known ✓ | P00918 | 3/20 | 0.56 |
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.54 |
| ▸ | MMP1 known ✓ | P03956 | 1/20 | 0.54 |
| ▸ | MMP8 known ✓ | P22894 | 1/20 | 0.54 |
| ▸ | MMP13 known ✓ | P45452 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 6/20 | 0.95 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.95 |
| ▸ | NT5E | P21589 | 1/20 | 0.95 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | MPO | P05164 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | AGO2 | Q9UKV8 | 2/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL482994 | 0.97 | TSHR (1.00) | TSHRALDH1A1NT5ELMNAMPO | |
| SCHEMBL24407 | 0.97 | TSHR (1.00) | TSHRALDH1A1NT5ELMNAMPO | |
| SCHEMBL30495973 | 0.97 | TSHR (1.00) | TSHRALDH1A1NT5ELMNAMPO | |
| SCHEMBL31415204 | 0.97 | TSHR (1.00) | TSHRALDH1A1NT5ELMNAMPO | |
| Nitrogen SCHEMBL29273170 | 0.95 | TSHR (0.86) | TSHRALDH1A1NT5ELMNAMPO | |
| Sulfuric Acid SCHEMBL10596856 | 0.95 | TSHR (0.95) | TSHRALDH1A1NT5ELMNAMPO | |
| SCHEMBL646074 | 0.95 | TSHR (0.95) | TSHRALDH1A1NT5ELMNAMPO | |
| SCHEMBL192816 | 0.95 | TSHR (0.95) | TSHRALDH1A1NT5ELMNAMPO | |
| SCHEMBL7766917 | 0.95 | TSHR (0.95) | TSHRALDH1A1NT5ELMNAMPO | |
| Water SCHEMBL8586611 | 0.95 | TSHR (0.95) | TSHRALDH1A1NT5ELMNAMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119241399-A | Benzenesulfonyl compound taking AR/AR-V7 double protein as target point and preparation method and application thereof | 上海应用技术大学 | 2025-01-03 | — | — | CN | claimed |
| CN-111574429-A | Carbazolyl-containing aromatic polyamine monomer and preparation method and application thereof | 上海华谊树脂有限公司 | 2020-08-25 | — | — | CN | claimed |
| CN-110735331-A | Preparation of cotton fiber anion modifier, anion modifier and dyeing process | 浙江亿得化工有限公司 | 2020-01-31 | — | — | CN | claimed |
| CN-117756796-A | Method for preparing thiamine nitrate or thiamine hydrochloride by direct oxidation of thiamine hydrochloride and application thereof | 江苏兄弟维生素有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-117393752-A | Sulfonic acid group MXene anode material and preparation method and application thereof | 南昌欣旺达新能源有限公司 | 2024-01-12 | — | — | CN | disclosed |
| US-20220113258-A1 | TEST PAPER KIT FOR RAPID GRADED QUANTITATIVE DETECTION OF AROMATIC PRIMARY AMINE CONTENT IN ACIDIC SOLUTION AND APPLICATION THEREOF | DALIAN UNIVERSITY OF TECHNOLOGY (CN) | 2022-04-14 | — | — | US | disclosed |
| CN-112161972-B | Detection test paper group for rapidly and quantitatively detecting aromatic primary amine content in acidic solution in grading manner and application thereof | 大连理工大学 | 2021-04-20 | — | — | CN | disclosed |
| CN-112161972-A | Detection test paper group for rapidly and quantitatively detecting aromatic primary amine content in acidic solution in grading manner and application thereof | 大连理工大学 | 2021-01-01 | — | — | CN | disclosed |
| EP-3351530-B1 | METHOD OF PRODUCING A SODIUM SALT OF (2,6-DICHLOROPHENYL)AMIDE CARBOPENTOXYSULPHANILIC ACID | TETS VIKTOR VENIAMINOVICH (RU) | 2020-08-12 | — | — | EP | disclosed |
| US-10584095-B2 | Method of producing a sodium salt of (2,6-dichlorophenyl)amide carbopentoxysulfanilic acid | Tets, Viktor Veniaminovich (RU) | 2020-03-10 | — | — | US | disclosed |
| CN-110735331-A | Preparation of cotton fiber anion modifier, anion modifier and dyeing process | 浙江亿得化工有限公司 | 2020-01-31 | — | — | CN | disclosed |
| US-20070011823-A1 | Novel 2,3-disubstituted primary para-phenylenediamines and process for oxidation dyeing of keratin fibers | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| EP-1463744-A4 | DEVICES AND METHODS FOR ISOLATING AND DETECTING SPECIFIC SUBSTANCES IN COMPLEX MATRICES | SAFETEST INC (US) | 2005-10-26 | — | — | EP | disclosed |
| EP-1463744-A2 | DEVICES AND METHODS FOR ISOLATING AND DETECTING SPECIFIC SUBSTANCES IN COMPLEX MATRICES | Safetest, Inc. (US) | 2004-10-06 | — | — | EP | disclosed |
| US-20030148354-A1 | Devices and methods for isolating and detecting specific substances in complex matrices | SAFTEST, INC. (US) | 2003-08-07 | — | — | US | disclosed |
| WO-2003054516-A2 | DEVICES AND METHODS FOR ISOLATING AND DETECTING SPECIFIC SUBSTANCES IN COMPLEX MATRICES | SAFETEST, INC. (US) | 2003-07-03 | — | — | WO | disclosed |
| CN-1031132-C | Carbocyclic adenosine analogs useful as immunosuppressants | MARION MERRELL DOW INC (US) | 1996-02-28 | — | — | CN | disclosed |
| CN-1059909-A | The carbocyclic ring neplanocin of new useful as immunosuppressants | MARION MERRELL DOW INC (US) | 1992-04-01 | — | — | CN | disclosed |
| US-4151164-A | Process for preparing 3-methoxy-4-(4'-aminobenzenesulfonamido)-1,2,5-thiadiazole | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1979-04-24 | — | — | US | disclosed |
| US-4006186-A | MULTISTAGE FROM A PHENYLSULFONYL CHLORIDE AND HYDRAZINE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070011823-A1 | Novel 2,3-disubstituted primary para-phenylenediamines and process for oxidation dyeing of keratin fibers | KRT18, VIM, CDC73 | HTR6 4524/4885CA2 773/4885GAA 4383/4885 |
| US-10584095-B2 | Method of producing a sodium salt of (2,6-dichlorophenyl)amide carbopentoxysulfanilic acid | CA6, CA2, CA4 | HTR6 483/4885CA2 2/4885GAA 404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.