Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | SCD5 | Q86SK9 | 6/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SCD | O00767 | 3/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1475692 | 0.86 | RAB9A (0.66) | RAB9ANPC1SCD5ALDH1A1CYP1A2 | |
| SCHEMBL4831915 | 0.75 | RAB9A (0.38) | RAB9ANPC1SCD5ALDH1A1CYP1A2 | |
| SCHEMBL1476803 | 0.70 | RAB9A (0.58) | RAB9ANPC1SCD5ALDH1A1CYP1A2 | |
| SCHEMBL28538566 | 0.67 | HRH3 (0.52) | F10CYP1A2KMT2AEPHX2MEN1 | |
| SCHEMBL18711874 | 0.65 | F10 (0.43) | F10EPHX2TSHR | |
| SCHEMBL1474547 | 0.64 | NOTUM (0.59) | RAB9ANPC1SCD5ALDH1A1CYP1A2 | |
| SCHEMBL13584814 | 0.63 | F10 (0.44) | F10KDM4E | |
| SCHEMBL13584816 | 0.63 | F10 (0.44) | F10KDM4E | |
| SCHEMBL1475114 | 0.63 | EPHX2 (0.54) | RAB9ANPC1ALDH1A1HPGDKMT2A | |
| SCHEMBL1177874 | 0.63 | RAB9A (0.64) | RAB9ANPC1ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971600-A1 | ISOXAZOLE DERIVATIVES AND USE THEREOF | SK Holdings Co., Ltd. (KR) | 2008-09-24 | — | — | EP | claimed |
| WO-2007078113-A1 | ISOXAZOLE DERIVATIVES AND USE THEREOF | SK HOLDINGS CO., LTD. (KR) | 2007-07-12 | — | — | WO | claimed |