Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29823450 | 0.83 | CXCR4 (0.58) | CXCR4ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL1878715 | 0.83 | CXCR4 (0.58) | CXCR4ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL1882689 | 0.81 | CXCR4 (0.56) | CXCR4ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL3315026 | 0.81 | CXCR4 (0.56) | CXCR4ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL3315031 | 0.81 | CXCR4 (0.56) | CXCR4ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL31722272 | 0.81 | CXCR4 (0.56) | CXCR4ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL1882687 | 0.81 | CXCR4 (0.56) | CXCR4ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL1871874 | 0.81 | CXCR4 (0.51) | CXCR4ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL29823621 | 0.81 | CXCR4 (0.51) | CXCR4ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL4063069 | 0.80 | MAOA (0.46) | CXCR4ALDH1A1L3MBTL1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1991221-A2 | METHODS FOR INCREASING BLOOD FLOW AND/OR PROMOTING TISSUE REGENERATION | Genzyme Corporation (US) | 2008-11-19 | — | — | EP | disclosed |
| WO-2007106063-A2 | METHODS FOR INCREASING BLOOD FLOW AND/OR PROMOTING TISSUE REGENERATION | GENZYME CORPORATION (US) | 2007-09-20 | — | — | WO | disclosed |