SCHEMBL4833244

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4833270	1.00	KMT2A (0.44)	KMT2AMEN1ALDH1A1USP2HTR2A
	SCHEMBL4833850	0.90	KMT2A (0.42)	KMT2AMEN1ALDH1A1USP2HTR2A
	SCHEMBL4834237	0.89	NPC1 (0.42)	KMT2AHTR2ACCNCCDK8LMNA
	SCHEMBL4834263	0.89	NPC1 (0.42)	KMT2AHTR2ACCNCCDK8LMNA
	SCHEMBL4834605	0.89	BTK (0.45)	KMT2AMEN1ALDH1A1USP2HTR2A
	SCHEMBL4833435	0.89	HDAC1 (0.44)	KMT2AMEN1HTR2ACCNCCDK8
	SCHEMBL4833418	0.89	HDAC1 (0.44)	KMT2AMEN1HTR2ACCNCCDK8
	SCHEMBL4827118	0.89	CCNC (0.47)	KMT2AMEN1CCNCCDK8MAPT
	SCHEMBL4827126	0.89	CCNC (0.47)	KMT2AMEN1CCNCCDK8MAPT
	SCHEMBL4833842	0.85	HTR2A (0.43)	KMT2AMEN1ALDH1A1USP2HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.