SCHEMBL483331

SCHEMBL483331

NC1CCc2cccnc2N1

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.37
HTR2C P28335 1/20 0.37
HTR2B P41595 1/20 0.37
PLAU P00749 1/20 0.36
IDH1 O75874 6/20 0.36
ADRA1A P35348 1/20 0.34
GSK3B P49841 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4183810 0.81 GSK3B (0.34) PLAUIDH1ADRA1AGSK3B
SCHEMBL15529909 0.79 IDH1 (0.39) HTR2AHTR2CHTR2BIDH1ADRA1A
SCHEMBL8039039 0.79 GSK3B (0.39) HTR2AHTR2CHTR2BIDH1ADRA1A
SCHEMBL16700662 0.76 IDH1 (0.40) HTR2AHTR2CHTR2BIDH1
SCHEMBL21905591 0.76 IDH1 (0.40) IDH1
SCHEMBL8325895 0.75 DRD2 (0.38) HTR2AHTR2CHTR2BIDH1GSK3B
SCHEMBL28153638 0.75 IDH1 (0.36) HTR2AHTR2CHTR2BIDH1ADRA1A
SCHEMBL18067769 0.75 IDH1 (0.36) HTR2AHTR2CHTR2BIDH1ADRA1A
SCHEMBL18068274 0.75 PDPK1 (0.38) HTR2AHTR2CHTR2BIDH1ADRA1A
SCHEMBL22509084 0.73 ANPEP (0.42) IDH1GSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150141877-A1 LED AND SHOCKWAVE THERAPY FOR TATTOO REMOVAL INREXREM INC. (US) 2015-05-21 US claimed
US-20140276246-A1 SYSTEM AND METHOD FOR TATTOO REMOVAL InrexRem 2014-09-18 US claimed
EP-1651190-B1 FORMULATIONS CONTAINING AN IMMUNE RESPONSE MODIFIER 3M INNOVATIVE PROPERTIES CO (US) 2012-09-19 EP claimed
US-7375180-B2 Methods and compositions related to IRM compounds and Toll-like receptor 8 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-05-20 US claimed
EP-1592302-A4 METHODS AND COMPOSITIONS RELATED TO IRM COMPOUNDS AND TOLL-LIKE RECEPTOR 8 3M INNOVATIVE PROPERTIES CO (US) 2007-04-25 EP claimed
US-7179253-B2 Method of tattoo removal 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-02-20 US claimed
WO-2006130399-A2 THERAPEUTIC COMBINATIONS AND METHODS INCLUDING IRM COMPOUNDS 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-12-07 WO claimed
EP-1603476-A2 METHOD OF TATTOO REMOVAL 3M Innovative Properties Company (US) 2005-12-14 EP claimed
EP-1592302-A2 METHODS AND COMPOSITIONS RELATED TO IRM COMPOUNDS AND TOLL-LIKE RECEPTOR 8 3M Innovative Properties Company (US) 2005-11-09 EP claimed
US-20050226878-A1 Therapeutic combinations and methods including IRM compounds 3M INNOVATIVE PROPERTIES COMPANY 2005-10-13 US claimed
WO-2004080292-A2 METHOD OF TATTOO REMOVAL 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-09-23 WO claimed
US-20040181211-A1 Method of tattoo removal 3M INNOVATIVE PROPERTIES COMPANY 2004-09-16 US claimed
WO-2004071459-A2 METHODS AND COMPOSITIONS RELATED TO IRM COMPOUNDS AND TOLL-LIKE RECEPTOR 8 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-08-26 WO claimed
US-20040162309-A1 Methods and compositions related to IRM compounds and toll-like receptor 8 3M INNOVATIVE PROPERTIES COMPANY 2004-08-19 US claimed
US-20250152703-A1 COMPOSITIONS FOR STIMULATION OF MAMMALIAN INNATE IMMUNE RESISTANCE TO PATHOGENS THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2025-05-15 US disclosed
US-12201684-B2 Compositions for stimulation of mammalian innate immune resistance to pathogens THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-01-21 US disclosed
US-20240417738-A1 IMMUNOTHERAPIES FOR THE TREATMENT OF CANCER OHIO STATE INNOVATION FOUNDATION 2024-12-19 US disclosed
US-20040202720-A1 Delivery of immune response modifier compounds using metal-containing particulate support materials 3M INNOVATIVE PROPERTIES COMPANY 2004-10-14 US disclosed
WO-2004071459-A2 METHODS AND COMPOSITIONS RELATED TO IRM COMPOUNDS AND TOLL-LIKE RECEPTOR 8 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-08-26 WO disclosed
US-20040162309-A1 Methods and compositions related to IRM compounds and toll-like receptor 8 3M INNOVATIVE PROPERTIES COMPANY 2004-08-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040202720-A1 Delivery of immune response modifier compounds using metal-containing particulate support materials MIF, IRF3, IRF2BP2 HTR2A 3595/4885HTR2C 4585/4885HTR2B 3817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.