Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.67 |
| ▸ | GSK3B | P49841 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.62 |
| ▸ | FEN1 | P39748 | 1/20 | 0.62 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL27878545 | 0.85 | TDP1 (0.67) | SMN1; SMN2MAPTL3MBTL1PTPN1GSK3B | |
| SCHEMBL27431671 | 0.85 | TDP1 (0.67) | SMN1; SMN2MAPTL3MBTL1PTPN1GSK3B | |
| SCHEMBL44898 | 0.85 | TDP1 (0.67) | SMN1; SMN2MAPTL3MBTL1PTPN1GSK3B | |
| SCHEMBL11868666 | 0.85 | TDP1 (0.67) | SMN1; SMN2MAPTL3MBTL1PTPN1GSK3B | |
| SCHEMBL27182280 | 0.84 | ERCC5 (0.77) | SMN1; SMN2MAPTL3MBTL1PTPN1GSK3B | |
| SCHEMBL11410208 | 0.83 | TDP1 (0.64) | SMN1; SMN2MAPTL3MBTL1PTPN1GSK3B | |
| Methane SCHEMBL506260 | 0.83 | TDP1 (0.64) | SMN1; SMN2MAPTL3MBTL1PTPN1GSK3B | |
| SCHEMBL10595732 | 0.83 | TDP1 (0.64) | SMN1; SMN2MAPTL3MBTL1PTPN1GSK3B | |
| Hydrogen Sulfide SCHEMBL843971 | 0.83 | TDP1 (0.64) | SMN1; SMN2MAPTL3MBTL1PTPN1GSK3B | |
| SCHEMBL3639678 | 0.83 | TDP1 (0.64) | SMN1; SMN2MAPTL3MBTL1PTPN1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109678788-B | 1, 2-diaryl indole, derivative and synthetic method thereof | 湘潭大学 | 2021-05-04 | — | — | CN | claimed |
| CN-109678788-A | A kind of 1,2- diaryl indoles, derivative and its synthetic method | 湘潭大学 | 2019-04-26 | — | — | CN | claimed |
| US-4217360-A | LUTEOLYTIC | SCHERING AKTIENGESELLSCHAFT (DE) | 1980-08-12 | — | — | US | claimed |
| US-20240198581-A2 | Parallelized 3D Lithography Using Multi-Beam, Multi-Color Light-Induced Polymerization | Karlsruher Institut für Technologie (DE) | 2024-06-20 | — | — | US | disclosed |
| US-11999098-B2 | Parallelized 3D lithography using multi-beam, multi-color light-induced polymerization | Karlsruher Institut für Technologie (DE) | 2024-06-04 | — | — | US | disclosed |
| US-20220055290-A1 | Parallelized 3D Lithography Using Multi-Beam, Multi-Color Light-Induced Polymerization | KARLSRUHER INST TECHNOLOGIE (DE) | 2022-02-24 | — | — | US | disclosed |
| EP-3898181-A1 | PARALLELISED 3D LITHOGRAPHY USING MUTI-BEAM, MULTI-COLOUR LIGHT-INDUCED POLYMERISATION | Karlsruher Institut für Technologie (DE) | 2021-10-27 | — | — | EP | disclosed |
| CN-109678788-B | 1, 2-diaryl indole, derivative and synthetic method thereof | 湘潭大学 | 2021-05-04 | — | — | CN | disclosed |
| US-20210008045-A1 | PANICINOTAM DERIVATIVE, PREPARATION METHOD AND USE THEREOF | OCEAN UNIVERSITY OF CHINA (CN) | 2021-01-14 | — | — | US | disclosed |
| CN-109678788-A | A kind of 1,2- diaryl indoles, derivative and its synthetic method | 湘潭大学 | 2019-04-26 | — | — | CN | disclosed |
| CN-104177241-B | Alkynyl diketone compound and synthetic method thereof | 华东师范大学 | 2017-01-11 | — | — | CN | disclosed |
| US-4536517-A | ANTIDIABETIC, ANTILIPEMIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1985-08-20 | — | — | US | disclosed |
| US-4307020-A | REACTING AN 0-HYDROXYACETOPHENONE WITH A GLYOXYLIC ACID | BAYER AKTIENGESELLSCHAFT (DE) | 1981-12-22 | — | — | US | disclosed |
| US-4289887-A | OPTICAL BRIGHTENERS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-09-15 | — | — | US | disclosed |
| US-4285965-A | FUNGICIDES AND INSECTICIDES FOR PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-08-25 | — | — | US | disclosed |
| EP-0000377-B1 | PROCESS FOR THE PREPARATION OF CHROMONE DERIVATIVES, NEW CHROMONE DERIVATIVES AND THEIR USE AS PLANT-PROTECTING AGENTS | BAYER AG (DE) | 1981-01-21 | — | — | EP | disclosed |
| EP-0019182-A1 | Benzofuran derivatives and their use as optical brighteners | BAYER AG (DE) | 1980-11-26 | — | — | EP | disclosed |
| US-4217360-A | LUTEOLYTIC | SCHERING AKTIENGESELLSCHAFT (DE) | 1980-08-12 | — | — | US | disclosed |
| US-4189498-A | FUNGICIDES, ARTHROPODICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-02-19 | — | — | US | disclosed |
| EP-0000377-A1 | Process for the preparation of chromone derivatives, new chromone derivatives and their use as plant-protecting agents | BAYER AG (DE) | 1979-01-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210008045-A1 | PANICINOTAM DERIVATIVE, PREPARATION METHOD AND USE THEREOF | TPMT, PBRM1, PGM2 | SMN1; SMN2 4172/4885MAPT 4/4885L3MBTL1 4171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.