Sugi Predict

Sugi Predict / Targets / PGM2

PGM2

Phosphopentomutase · Q96G03 · PGM2 on Sugi Atlas →

0 patent compounds predicted against PGM2, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to PGM2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
ALL SCTped FORUM - Pharmacogenomic Study (add-on Study) PHASE4UNKNOWN
Study to Evaluate Efficacy and Safety of Elamipretide in Subjects With Primary Mitochondrial Disease From Nuclear DNA Mutations (nPMD) PHASE3COMPLETED
A Study of KRN23 in Pediatric Patients With X-linked Hypophosphatemic Rickets/Osteomalacia PHASE3COMPLETED
24-Week Study to Assess the PD, Safety, Tolerability, and PK of GLM101 in Participants With PMM2-CDG PHASE2COMPLETED
Open-Label Extension Study to Assess GLM101 in PMM2-CDG Patients PHASE2ENROLLING_BY_INVITATION
The Effect of Triheptanoin on Fatty Acid Oxidation and Exercise Tolerance in Patients With Glycogenoses PHASE2COMPLETED
Safety and Efficacy Study of ENB-0040 in Juvenile Patients With Hypophosphatasia (HPP) PHASE2WITHDRAWN
Unraveling Genetics of HypoPhosPhatasia (HPP Genetics) nanCOMPLETED
GSD VI and GSD IX Natural History nanRECRUITING
Natural History Study Protocol in PMM2-CDG (CDG-Ia) nanACTIVE_NOT_RECRUITING
Studying Phosphorus Metabolism nanCOMPLETED
Institution of an Italian Multicenter Database of Patients Affected by Diseases of Phosphate Metabolism nanNOT_YET_RECRUITING
'Glycogen Storage Diseases (GSDs) in Indian Children- Establishing an Indian GSD (I-GSD) Registry' nanRECRUITING
MyRareDiet A Novel Diet Tracking Tool nanNOT_YET_RECRUITING
Implementing Preemptive Pharmacogenomic Testing for Colorectal Cancer Patients in a Community Oncology Clinic nanCOMPLETED
Genetic Studies of Lysosomal Storage Disorders nanENROLLING_BY_INVITATION
Foci of Tumor Heterogeneity in Diffuse Low-Grade Gliomas nanCOMPLETED
Genetic Study of Families Affected by Paget's Disease of Bone nanCOMPLETED
Glycine and Magnesium+Thiamine for the Treatment of Primary Ciliary Dyskinesia nanRECRUITING
Pattern of Metabolic Causes of Neonatal Hypoglycemia nanUNKNOWN
Biomarkers in Exhaled Breath Condensates in Acute Lung Injury: Early Detection and Outcome Predictors nanUNKNOWN
Characterisation of Adult-Onset Hypophosphatasia nanCOMPLETED
Screening of Lysosomal Storage Disorders Diseases in Minority Groups nanUNKNOWN
Recurrent Acute Myocarditis Registry nanUNKNOWN
McArdle Disease Treatment by Ketogenic Diet nanCOMPLETED
GDF-15 as a Biomarker for Mitochondrial Disease nanCOMPLETED
Retrospective Study of Adult Patients With Inborn Errors of Metabolism in Switzerland nanCOMPLETED
Rare Kidney Stone Consortium Biobank nanRECRUITING
Using Next-generation Sequencing in the Diagnosis of Epilepsy and/or Intellectual Disability in a Pediatric Cohorte nanCOMPLETED
The Effect of Monoallelic Variants in the ALPL Gene on the Natural Course of Hypophosphatasia in Russia nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a PGM2 binder may also engage these)

ProteinNameSimilarity
Q5RFI8 — 1.000 Q5RFI8 →
Q7TSV4 — 0.993 Q7TSV4 →
Q5R979 — 0.976 Q5R979 →
Q4R5E4 — 0.975 Q4R5E4 →
P00949 — 0.974 P00949 →
Q6PCE3 — 0.971 Q6PCE3 →
P36871 — 0.970 P36871 →
Q08DP0 — 0.969 Q08DP0 →
Q8BZF8 — 0.967 Q8BZF8 →
Q8CAA7 — 0.967 Q8CAA7 →
Q9D0F9 — 0.964 Q9D0F9 →
P38652 — 0.963 P38652 →
Q9ZSQ4 — 0.962 Q9ZSQ4 →
D3ZVR9 — 0.961 D3ZVR9 →
GLS2 Glutaminase liver isoform, mitochondrial 0.960 landscape →
Q15124 — 0.960 Q15124 →
TPP2 Tripeptidyl-peptidase 2 0.957 landscape →
Q9SGC1 — 0.956 Q9SGC1 →
Q5I0K3 — 0.956 Q5I0K3 →
P13439 — 0.956 P13439 →
P93804 — 0.955 P93804 →
P28492 — 0.954 P28492 →
Q91WC3 — 0.954 Q91WC3 →
Q64560 — 0.954 Q64560 →
Q9ER35 — 0.953 Q9ER35 →
UBA3 NEDD8-activating enzyme E1 catalytic subunit 0.953 landscape →
P93805 — 0.953 P93805 →
A5PK39 — 0.953 A5PK39 →
Q5R514 — 0.952 Q5R514 →
Q8R4N0 — 0.952 Q8R4N0 →