Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 11/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | MAP3K9 | P80192 | 2/20 | 0.38 |
| ▸ | MAP3K10 | Q02779 | 2/20 | 0.38 |
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7200645 | 0.86 | CA1 (0.45) | CA1CA2CA4CA6PARP1 | |
| SCHEMBL4954076 | 0.80 | CA1 (0.51) | CA1CA2CA4CA6PARP1 | |
| SCHEMBL2763222 | 0.77 | PARP1 (0.70) | CA1CA2CA4CA6PARP1 | |
| SCHEMBL4863324 | 0.76 | KMT2A (0.45) | CA1CA2CA4CA6PARP1 | |
| SCHEMBL2763163 | 0.74 | PARP1 (0.46) | CA1CA2CA4CA6PARP1 | |
| SCHEMBL6899170 | 0.72 | PARP1 (0.45) | CA1CA2CA4CA6PARP1 | |
| SCHEMBL2784194 | 0.71 | CA1 (0.39) | CA1CA2CA4CA6PARP1 | |
| SCHEMBL30341585 | 0.69 | PNMT (0.49) | CA1CA2CA4CA6MEN1 | |
| SCHEMBL1509311 | 0.69 | PNMT (0.49) | CA1CA2CA4CA6MEN1 | |
| Hydrochloric Acid SCHEMBL2870709 | 0.68 | PNMT (0.47) | CA1CA2CA4CA6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784186-A4 | METHODS FOR TREATING OR PREVENTING ERECTILE DYSFUNCTION OR URINARY INCONTINENCE | INOTEK PHARMACEUTICALS CORP (US) | 2008-05-14 | — | — | EP | disclosed |
| EP-1784186-A2 | METHODS FOR TREATING OR PREVENTING ERECTILE DYSFUNCTION OR URINARY INCONTINENCE | Inotek Pharmaceuticals Corporation (US) | 2007-05-16 | — | — | EP | disclosed |
| WO-2006009718-A2 | METHODS FOR TREATING OR PREVENTING ERECTILE DYSFUNCTION OR URINARY INCONTINENCE | INOTEK PHARMACEUTICALS CORPORATION (US) | 2006-01-26 | — | — | WO | disclosed |