Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | CFD | P00746 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL310923 | 0.87 | MAOB (0.48) | MAOBNR4A2SMN1; SMN2FFAR4DHODH | |
| SCHEMBL483622 | 0.87 | MAOB (0.48) | MAOBNR4A2SMN1; SMN2FFAR4DHODH | |
| SCHEMBL17873367 | 0.87 | MAOB (0.48) | MAOBNR4A2SMN1; SMN2FFAR4DHODH | |
| SCHEMBL483467 | 0.74 | JAK2 (0.46) | MAOBMRGPRX4NR4A2NR1H4SMPD1 | |
| SCHEMBL310304 | 0.74 | MAOB (0.52) | MAOBSMN1; SMN2 | |
| SCHEMBL2836867 | 0.73 | MRGPRX4 (0.49) | MAOBMRGPRX4NR4A2NR1H4SMN1; SMN2 | |
| SCHEMBL379281 | 0.72 | MAOB (0.67) | MAOBMRGPRX4NR4A2NR1H4FFAR4 | |
| SCHEMBL483664 | 0.71 | MAOB (0.47) | MAOBNR4A2SMN1; SMN2FFAR4DHODH | |
| SCHEMBL16990090 | 0.71 | TMPRSS15 (0.58) | MAOBMRGPRX4NR4A2NR1H4KMT2A | |
| SCHEMBL16990054 | 0.71 | TMPRSS15 (0.58) | MAOBMRGPRX4NR4A2NR1H4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153623-B2 | Compounds | Convergence Pharmaceuticals Limited (GB) | 2012-04-10 | — | — | US | disclosed |
| EP-1934176-B1 | QUATERNARY ALPHA-AMINOCARBOXAMIDE DERIVATIVES AS MODULATORS OF VOLTAGE-GATED SODIUM CHANNELS | GLAXO GROUP LTD (GB) | 2012-02-01 | — | — | EP | disclosed |