SCHEMBL4835973

SCHEMBL4835973

O=C1c2c(c(O)c3ccccc3c2O)C(=O)c2c1c(O)c1ccccc1c2O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.50
KMT2A Q03164 6/20 0.50
KDM4E B2RXH2 5/20 0.50
MEN1 O00255 4/20 0.50
TDP1 Q9NUW8 3/20 0.50
RECQL P46063 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
THRB P10828 2/20 0.50
NPC1 O15118 1/20 0.50
POLB P06746 1/20 0.50
RAB9A P51151 1/20 0.50
BLM P54132 1/20 0.50
MCL1 Q07820 1/20 0.50
ALDH1A1 P00352 4/20 0.45
MAOA P21397 3/20 0.45
HPGD P15428 2/20 0.45
ALOX15 P16050 2/20 0.45
MAOB P27338 2/20 0.45
MAPK1 P28482 2/20 0.45
HSD17B10 Q99714 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL497005 0.87 MEN1 (0.61) MAPTKMT2AKDM4EMEN1TDP1
SCHEMBL29883673 0.87 MEN1 (0.61) MAPTKMT2AKDM4EMEN1TDP1
SCHEMBL2639287 0.79 NQO1 (0.60) MAPTKMT2AKDM4EMEN1TDP1
SCHEMBL2908244 0.79 MEN1 (0.47) MAPTKMT2AKDM4EMEN1TDP1
SCHEMBL31218584 0.77 KDM4E (0.61) MAPTKMT2AKDM4EMEN1TDP1
SCHEMBL375358 0.77 KDM4E (0.61) MAPTKMT2AKDM4EMEN1TDP1
SCHEMBL29612818 0.77 KDM4E (0.61) MAPTKMT2AKDM4EMEN1TDP1
SCHEMBL11716746 0.77 DAPK1 (0.58) MAPTKMT2AKDM4EMEN1TDP1
SCHEMBL11141991 0.77 MEN1 (0.55) MAPTKMT2AKDM4EMEN1TDP1
SCHEMBL31171154 0.77 MAPT (0.54) MAPTKMT2AKDM4EMEN1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7439407-B2 Fluorinated pentacene derivative and method of producing same KANTO DENTA KOGYO CO., LTD. (JP) 2008-10-21 US disclosed
US-7439407-B2 Fluorinated pentacene derivative and method of producing same KANTO DENTA KOGYO CO., LTD. (JP) 2008-10-21 US disclosed
US-7439407-B2 Fluorinated pentacene derivative and method of producing same KANTO DENTA KOGYO CO., LTD. (JP) 2008-10-21 US disclosed
US-20070083067-A1 Fluorinated pentacene derivative and method of producing same KANTO DENKA KOGYO CO. LTD. (JP) 2007-04-12 US disclosed
US-20070083067-A1 Fluorinated pentacene derivative and method of producing same KANTO DENKA KOGYO CO. LTD. (JP) 2007-04-12 US disclosed
US-20070083067-A1 Fluorinated pentacene derivative and method of producing same KANTO DENKA KOGYO CO. LTD. (JP) 2007-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070083067-A1 Fluorinated pentacene derivative and method of producing same FAR1, FAM162A, FFAR4 MAPT 4726/4885KMT2A 4146/4885KDM4E 3554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.