SCHEMBL497005

SCHEMBL497005

O=C1c2ccccc2C(=O)c2c1c(O)c1ccccc1c2O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 8/20 0.61
KMT2A Q03164 8/20 0.61
MAOA P21397 6/20 0.61
MAPT P10636 6/20 0.61
MAPK1 P28482 4/20 0.61
DAPK1 P53355 3/20 0.61
HPGD P15428 3/20 0.61
KDM4E B2RXH2 3/20 0.61
RECQL P46063 3/20 0.61
ALDH1A1 P00352 3/20 0.61
TDP1 Q9NUW8 3/20 0.61
CYP3A4 P08684 2/20 0.61
ALOX15 P16050 2/20 0.61
ALOX12 P18054 2/20 0.61
CYP1B1 Q16678 2/20 0.61
HSD17B10 Q99714 2/20 0.61
TTR P02766 2/20 0.61
L3MBTL1 Q9Y468 2/20 0.61
CYP1A1 P04798 1/20 0.61
HSPD1 P10809 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29883673 1.00 MEN1 (0.61) MEN1KMT2AMAOAMAPTMAPK1
SCHEMBL11141991 0.89 MEN1 (0.55) MEN1KMT2AMAOAMAPTMAPK1
SCHEMBL11716746 0.88 DAPK1 (0.58) MEN1KMT2AMAOAMAPTMAPK1
SCHEMBL4835973 0.87 MAPT (0.50) MEN1KMT2AMAOAMAPTMAPK1
SCHEMBL899150 0.87 MEN1 (0.68) MEN1KMT2AMAOAMAPTMAPK1
Anthraquinone SCHEMBL10595870 0.85 MEN1 (0.63) MEN1KMT2AMAOAMAPTMAPK1
SCHEMBL10885940 0.84 MAOA (0.55) MEN1KMT2AMAOAMAPTMAPK1
SCHEMBL8581315 0.83 MEN1 (0.63) MEN1KMT2AMAOAMAPTMAPK1
SCHEMBL9296456 0.81 MEN1 (0.56) MEN1KMT2AMAOAMAPTMAPK1
SCHEMBL2908244 0.81 MEN1 (0.47) MEN1KMT2AMAOAMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115117467-A Acid water system all-organic symmetrical battery based on dihydroxynaphthalene dione derivative 常州大学 2022-09-27 CN claimed
US-9039946-B2 Reversibly thermochromic compositions BASF SE (DE) 2015-05-26 US claimed
EP-1888705-B1 Reversibly thermochromic compositions BASF SE (DE) 2010-08-18 EP claimed
US-20090302284-A1 Reversibly Thermochromic Compositions CIBA CORPORATION 2009-12-10 US claimed
US-20090082574-A1 Metallacycles and methods of making the same ACADEMIA SINICA (TW) 2009-03-26 US claimed
EP-1888705-A1 REVERSIBLY THERMOCHROMIC COMPOSITIONS Ciba Specialty Chemicals Holding, Inc. (CH) 2008-02-20 EP claimed
WO-2006131465-A1 REVERSIBLY THERMOCHROMIC COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-12-14 WO claimed
WO-2026078075-A1 METAL COORDINATION COMPLEXES CAMBRIDGE ENTERPRISE LIMITED (GB) 2026-04-16 WO disclosed
CN-115117467-A Acid water system all-organic symmetrical battery based on dihydroxynaphthalene dione derivative 常州大学 2022-09-27 CN disclosed
EP-2888116-B1 SECURITY AND/OR VALUE DOCUMENT CONTAINING A VISUAL SWITCHABLE WINDOW WITH A HOLOGRAM COVESTRO DEUTSCHLAND AG (DE) 2016-09-21 EP disclosed
US-9039946-B2 Reversibly thermochromic compositions BASF SE (DE) 2015-05-26 US disclosed
US-9039946-B2 Reversibly thermochromic compositions BASF SE (DE) 2015-05-26 US disclosed
CN-101189318-B Reversibly thermochromic compositions CIBA SC HOLDING AG 2012-06-20 CN disclosed
WO-2006131465-A1 REVERSIBLY THERMOCHROMIC COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-12-14 WO disclosed
WO-2006131465-A1 REVERSIBLY THERMOCHROMIC COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-12-14 WO disclosed
WO-2006121522-A2 IMPLANTABLE SENSORS AND PUMPS, ANTI-SCARRING AGENTS, AND THERAPEUTIC COMPOSITIONS ANGIOTECH INTERNATIONAL AG (CH) 2006-11-16 WO disclosed
WO-2006121518-A2 ELECTRICAL DEVICES, ANTI-SCARRING AGENTS, AND THERAPEUTIC COMPOSITIONS ANGIOTECH INTERNATIONAL AG (CH) 2006-11-16 WO disclosed
US-20060207891-A1 System and method for electrochemical detection of biological compounds HANDYLAB, INC. (US) 2006-09-21 US disclosed
WO-2004094986-A2 SYSTEM AND METHOD FOR ELECTROCHEMICAL DETECTION OF BIOLOGICAL COMPOUNDS HANDYLAB, INC. (US) 2004-11-04 WO disclosed
US-4739062-A REACTING AN AROMATIC COMPOUND WITH DICARBOXYLIC ACID COMPOUND USING METAL HALIDE CATALYST CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1988-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090302284-A1 Reversibly Thermochromic Compositions DHCR7, NES, DUT MEN1 946/4885KMT2A 1932/4885MAOA 3289/4885
US-20090082574-A1 Metallacycles and methods of making the same SOD1, PMS2, MEN1 MEN1 3/4885KMT2A 686/4885MAOA 1121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.