Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.44 |
| ▸ | NQO2 | P16083 | 3/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.39 |
| ▸ | TUBB | P07437 | 3/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5248756 | 0.81 | MAPT (0.41) | ACHEKDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL772484 | 0.79 | CA2 (0.50) | TUBB1NQO2TUBB4ATUBBTUBA3C | |
| SCHEMBL30171329 | 0.79 | CA2 (0.50) | TUBB1NQO2TUBB4ATUBBTUBA3C | |
| SCHEMBL9109330 | 0.77 | TUBB1 (0.47) | TUBB1NQO2TUBB4ATUBBTUBA3C | |
| SCHEMBL29209891 | 0.77 | ALOX5AP (0.38) | TUBB1NQO2TUBB4ATUBBTUBA3C | |
| SCHEMBL147312 | 0.76 | TUBB1 (0.46) | TUBB1NQO2TUBB4ATUBBTUBA3C | |
| SCHEMBL127769 | 0.75 | CA2 (0.55) | TUBB1NQO2TUBB4ATUBBTUBA3C | |
| SCHEMBL2583686 | 0.74 | ERN1 (0.56) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL624239 | 0.74 | ALOX5AP (0.46) | TUBB1NQO2TUBB4ATUBBTUBA3C | |
| SCHEMBL31096354 | 0.74 | ERN1 (0.56) | TUBB1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368463-B2 | Substituted 4-amino-1-benzylpiperidine compounds | THERAVANCE, INC. (US) | 2008-05-06 | — | — | US | disclosed |