Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | LDHB | P07195 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | CALML3 | P27482 | 1/20 | 0.39 |
| ▸ | SDHA | P31040 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL483657 | 0.89 | NPC1 (0.49) | NPC1ALDH1A1SMN1; SMN2HPGDLMNA | |
| SCHEMBL483955 | 0.86 | MLYCD (0.45) | NPC1ALDH1A1SMN1; SMN2HPGDLMNA | |
| SCHEMBL483873 | 0.86 | NPC1 (0.43) | NPC1ALDH1A1SMN1; SMN2HPGDLMNA | |
| SCHEMBL483968 | 0.85 | NPC1 (0.44) | NPC1ALDH1A1SMN1; SMN2HPGDLMNA | |
| SCHEMBL483670 | 0.85 | NPC1 (0.41) | NPC1ALDH1A1SMN1; SMN2HPGDLMNA | |
| SCHEMBL483922 | 0.85 | NPC1 (0.47) | NPC1ALDH1A1SMN1; SMN2HPGDLMNA | |
| SCHEMBL483675 | 0.82 | NPC1 (0.51) | NPC1ALDH1A1SMN1; SMN2HPGDLMNA | |
| SCHEMBL483655 | 0.82 | MAOB (0.44) | NPC1ALDH1A1SMN1; SMN2HPGDLMNA | |
| SCHEMBL483861 | 0.82 | MAPT (0.40) | NPC1ALDH1A1SMN1; SMN2HPGDLMNA | |
| SCHEMBL8425426 | 0.78 | NPC1 (0.50) | NPC1ALDH1A1SMN1; SMN2HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2072505-B1 | A process for the preparation of oxazolidinone derivatives | DIPHARMA FRANCIS SRL (IT) | 2012-02-01 | — | — | EP | claimed |
| EP-2072505-A2 | A process for the preparation of oxazolidinone derivatives | Dipharma Francis S.r.l. (IT) | 2009-06-24 | — | — | EP | claimed |
| US-20090156806-A1 | Process for the Preparation of Oxazolidinone Derivatives | DIPHARMA FRANCIS S.R.I. (IT) | 2009-06-18 | — | — | US | claimed |
| EP-2072505-B1 | A process for the preparation of oxazolidinone derivatives | DIPHARMA FRANCIS SRL (IT) | 2012-02-01 | — | — | EP | disclosed |
| EP-2072505-A2 | A process for the preparation of oxazolidinone derivatives | Dipharma Francis S.r.l. (IT) | 2009-06-24 | — | — | EP | disclosed |
| US-20090156806-A1 | Process for the Preparation of Oxazolidinone Derivatives | DIPHARMA FRANCIS S.R.I. (IT) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156806-A1 | Process for the Preparation of Oxazolidinone Derivatives | OXA1L, AAAS, MLYCD | NPC1 4601/4885ALDH1A1 688/4885SMN1; SMN2 2136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.