Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 2/20 | 0.51 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.51 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.51 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.51 |
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HRH2 | P25021 | 1/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3864342 | 0.89 | TLR7 (0.57) | PI4KAPI4K2BPI4K2API4KBTLR7 | |
| SCHEMBL10744495 | 0.80 | ADORA2A (0.51) | PI4KAPI4K2BPI4K2API4KBTLR7 | |
| SCHEMBL10743830 | 0.77 | ADORA2A (0.58) | PI4KAPI4K2BPI4K2API4KBTLR7 | |
| SCHEMBL3863667 | 0.76 | PDPK1 (0.47) | PI4KAPI4K2BPI4K2API4KBALOX12 | |
| SCHEMBL4753594 | 0.74 | TLR7 (0.59) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL20741451 | 0.74 | TLR7 (0.50) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL3183969 | 0.73 | TLR7 (0.62) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL6030934 | 0.73 | TLR7 (0.59) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL20741465 | 0.73 | TLR7 (0.49) | PI4KAPI4K2BPI4K2API4KBTLR7 | |
| SCHEMBL6698894 | 0.72 | TLR7 (0.51) | TLR7ADORA2ALMNAPOLBHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411521-A1 | COMPOSITIONS FOR STIMULATION OF MAMMALIAN INNATE IMMUNE RESISTANCE TO PATHOGENS | The Board of Regents of The University of Texas System (US) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010111485-A1 | COMPOSITIONS FOR STIMULATION OF MAMMALIAN INNATE IMMUNE RESISTANCE TO PATHOGENS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2010-09-30 | — | — | WO | disclosed |