SCHEMBL3864342

SCHEMBL3864342

Nc1nc2ccccc2c2c1ncn2-c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 6/20 0.57
ADORA2A P29274 5/20 0.57
LMNA P02545 1/20 0.57
POLB P06746 1/20 0.57
HRH2 P25021 1/20 0.57
ADRA1D P25100 1/20 0.57
HTR2A P28223 1/20 0.57
ADRA1A P35348 1/20 0.57
NUDT1 P36639 1/20 0.57
HTR2B P41595 1/20 0.57
PDE4D Q08499 1/20 0.57
KCNH2 Q12809 1/20 0.57
ADORA3 P0DMS8 4/20 0.50
ADORA1 P30542 2/20 0.50
EGFR P00533 1/20 0.49
PI4KA P42356 1/20 0.49
PI4K2B Q8TCG2 1/20 0.49
PI4K2A Q9BTU6 1/20 0.49
PI4KB Q9UBF8 1/20 0.49
FGFR1 P11362 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10744495 0.90 ADORA2A (0.51) TLR7ADORA2ALMNAPOLBHRH2
SCHEMBL483671 0.89 PI4KA (0.51) TLR7ADORA2ALMNAPOLBHRH2
SCHEMBL10743830 0.87 ADORA2A (0.58) TLR7ADORA2ALMNAPOLBHRH2
SCHEMBL10731424 0.81 FGFR1 (0.46) TLR7ADORA2ALMNAPOLBHRH2
SCHEMBL4753594 0.81 TLR7 (0.59) TLR7ADORA2ALMNAPOLBHRH2
SCHEMBL20741451 0.80 TLR7 (0.50) TLR7ADORA2ALMNAPOLBHRH2
SCHEMBL15906393 0.80 FGFR1 (0.46) LMNAPDE4DEGFRPI4KAPI4K2B
SCHEMBL6030934 0.79 TLR7 (0.59) TLR7ADORA2ALMNAPOLBHRH2
SCHEMBL3183969 0.79 TLR7 (0.62) TLR7ADORA2ALMNAPOLBHRH2
SCHEMBL20741465 0.79 TLR7 (0.49) TLR7ADORA2ALMNAPOLBHRH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11472800-B2 Organic compound and organic electroluminescent device comprising the same DOOSAN SOLUS CO., LTD. (KR) 2022-10-18 US disclosed
US-20190263806-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DOOSAN CORPORATION (KR) 2019-08-29 US disclosed
US-20190263806-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DOOSAN CORPORATION (KR) 2019-08-29 US disclosed
US-7598382-B2 Aryl substituted imidazoquinolines COLEY PHARMACEUTICAL GROUP, INC. (US) 2009-10-06 US disclosed
US-7091214-B2 Aryl substituted Imidazoquinolines 3M INNOVATIVE PROPERTIES CO. (US) 2006-08-15 US disclosed
US-20060111387-A1 ARYL SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES COMPANY 2006-05-25 US disclosed
US-4689338-A 1H-Imidazo[4,5-c]quinolin-4-amines and antiviral use RIKER LABORATORIES, INC. (US) 1987-08-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11472800-B2 Organic compound and organic electroluminescent device comprising the same VDAC1, OR10J3, VDAC2 TLR7 3860/4885ADORA2A 4400/4885LMNA 1909/4885
US-20190263806-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME VDAC1, OR10J3, VDAC2 TLR7 3860/4885ADORA2A 4400/4885LMNA 1909/4885
US-20060111387-A1 ARYL SUBSTITUTED IMIDAZOQUINOLINES IL2, IFNG, IRF3 TLR7 68/4885ADORA2A 2283/4885LMNA 4453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.